GO Annotations Graph

• Symbol: Lonp1
• Name: lon peptidase 1, mitochondrial
• ID: MGI:1921392

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043531	ADP binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	IDA	J:82846
Molecular Function	GO:0004176	ATP-dependent peptidase activity	ISO	J:155856
Molecular Function	GO:0004176	ATP-dependent peptidase activity	ISO	J:164563
Molecular Function	GO:0004176	ATP-dependent peptidase activity	IDA	J:82846
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0070182	DNA polymerase binding	ISO	J:164563
Molecular Function	GO:0051880	G-quadruplex DNA binding	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0043560	insulin receptor substrate binding	IPI	J:230404
Molecular Function	GO:0001018	mitochondrial promoter sequence-specific DNA binding	IDA	J:82846
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0042731	PH domain binding	IPI	J:230404
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0004252	serine-type endopeptidase activity	IEA	J:72247
Molecular Function	GO:0004252	serine-type endopeptidase activity	IEA	J:72245
Molecular Function	GO:0008236	serine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0003697	single-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0003697	single-stranded DNA binding	IDA	J:82846
Molecular Function	GO:0003727	single-stranded RNA binding	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005759	mitochondrial matrix	ISO	J:155856
Cellular Component	GO:0005759	mitochondrial matrix	ISO	J:164563
Cellular Component	GO:0005759	mitochondrial matrix	IBA	J:265628
Cellular Component	GO:0042645	mitochondrial nucleoid	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:82846
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Biological Process	GO:0034599	cellular response to oxidative stress	ISO	J:164563
Biological Process	GO:0051131	chaperone-mediated protein complex assembly	IBA	J:265628
Biological Process	GO:0007005	mitochondrion organization	ISO	J:164563
Biological Process	GO:0007005	mitochondrion organization	IBA	J:265628
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	IDA	J:230404
Biological Process	GO:0070407	oxidation-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0030163	protein catabolic process	ISO	J:155856
Biological Process	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	IBA	J:265628
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:155856
Biological Process	GO:0006508	proteolysis	IDA	J:82846
Biological Process	GO:0051603	proteolysis involved in protein catabolic process	ISO	J:164563
Biological Process	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	IDA	J:230404