GO Annotations Graph

• Symbol: Errfi1
• Name: ERBB receptor feedback inhibitor 1
• ID: MGI:1921405

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019900	kinase binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0017124	SH3 domain binding	ISO	J:155856
Molecular Function	GO:0031267	small GTPase binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:109556
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:73065
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	IDA	J:109556
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Biological Process	GO:0048286	lung alveolus development	IMP	J:153715
Biological Process	GO:0060428	lung epithelium development	IMP	J:153715
Biological Process	GO:0060426	lung vasculature development	IMP	J:153715
Biological Process	GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress	ISO	J:155856
Biological Process	GO:0032966	negative regulation of collagen biosynthetic process	ISO	J:155856
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	IMP	J:153715
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	IMP	J:109556
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	ISO	J:164563
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	ISO	J:155856
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	ISO	J:155856
Biological Process	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	ISO	J:155856
Biological Process	GO:0031953	negative regulation of protein autophosphorylation	ISO	J:164563
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:155856
Biological Process	GO:0045616	regulation of keratinocyte differentiation	IMP	J:109556
Biological Process	GO:0045616	regulation of keratinocyte differentiation	IBA	J:265628
Biological Process	GO:0061469	regulation of type B pancreatic cell proliferation	ISO	J:155856
Biological Process	GO:0043589	skin morphogenesis	IMP	J:109556
Biological Process	GO:0031098	stress-activated protein kinase signaling cascade	ISO	J:73065