GO Annotations Graph

• Symbol: Xrcc3
• Name: X-ray repair complementing defective repair in Chinese hamster cells 3
• ID: MGI:1921585

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0140664	ATP-dependent DNA damage sensor activity	IEA	J:72247
Molecular Function	GO:0008821	crossover junction DNA endonuclease activity	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0000400	four-way junction DNA binding	ISO	J:164563
Molecular Function	GO:0000400	four-way junction DNA binding	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0033065	Rad51C-XRCC3 complex	ISO	J:164563
Cellular Component	GO:0033065	Rad51C-XRCC3 complex	IBA	J:265628
Cellular Component	GO:0005657	replication fork	ISO	J:164563
Cellular Component	GO:0005657	replication fork	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006310	DNA recombination	IEA	J:60000
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0045003	double-strand break repair via synthesis-dependent strand annealing	IBA	J:265628
Biological Process	GO:0036297	interstrand cross-link repair	ISO	J:164563
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	ISO	J:164563
Biological Process	GO:0010824	regulation of centrosome duplication	ISO	J:164563
Biological Process	GO:0071140	resolution of mitotic recombination intermediates	ISO	J:164563
Biological Process	GO:0071140	resolution of mitotic recombination intermediates	IBA	J:265628
Biological Process	GO:0090656	t-circle formation	ISO	J:164563
Biological Process	GO:0090656	t-circle formation	IBA	J:265628
Biological Process	GO:0000722	telomere maintenance via recombination	ISO	J:164563
Biological Process	GO:0000722	telomere maintenance via recombination	IBA	J:265628
Biological Process	GO:0090737	telomere maintenance via telomere trimming	ISO	J:164563