GO Annotations Graph

• Symbol: Rptor
• Name: regulatory associated protein of MTOR, complex 1
• ID: MGI:1921620

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:139950
Molecular Function	GO:0005515	protein binding	IPI	J:128527
Molecular Function	GO:0005515	protein binding	IPI	J:167176
Molecular Function	GO:0005515	protein binding	IPI	J:201589
Molecular Function	GO:0005515	protein binding	IPI	J:164024
Molecular Function	GO:0030295	protein kinase activator activity	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0030291	protein serine/threonine kinase inhibitor activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:164563
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	IBA	J:265628
Molecular Function	GO:0001002	RNA polymerase III type 1 promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0001003	RNA polymerase III type 2 promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0001006	RNA polymerase III type 3 promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0001156	TFIIIC-class transcription factor complex binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0031931	TORC1 complex	ISO	J:164563
Cellular Component	GO:0031931	TORC1 complex	IBA	J:265628
Cellular Component	GO:0031931	TORC1 complex	ISO	J:93907
Biological Process	GO:0071230	cellular response to amino acid stimulus	ISO	J:164563
Biological Process	GO:0071230	cellular response to amino acid stimulus	IBA	J:265628
Biological Process	GO:0071456	cellular response to hypoxia	NAS	J:320285
Biological Process	GO:0071233	cellular response to leucine	ISO	J:164563
Biological Process	GO:0031669	cellular response to nutrient levels	NAS	J:319972
Biological Process	GO:0031669	cellular response to nutrient levels	ISO	J:164563
Biological Process	GO:0071470	cellular response to osmotic stress	NAS	J:320285
Biological Process	GO:0009267	cellular response to starvation	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	NAS	J:320285
Biological Process	GO:0010507	negative regulation of autophagy	NAS	J:320286
Biological Process	GO:0046676	negative regulation of insulin secretion	IMP	J:219062
Biological Process	GO:0016310	phosphorylation	ISO	J:164563
Biological Process	GO:0030307	positive regulation of cell growth	NAS	J:319682
Biological Process	GO:0030307	positive regulation of cell growth	ISO	J:164563
Biological Process	GO:0030307	positive regulation of cell growth	IBA	J:265628
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:155856
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0045821	positive regulation of glycolytic process	NAS	J:163259
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	NAS	J:163259
Biological Process	GO:1905857	positive regulation of pentose-phosphate shunt	NAS	J:163259
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	ISO	J:164563
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	IBA	J:265628
Biological Process	GO:0032008	positive regulation of TOR signaling	ISO	J:164563
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	ISO	J:164563
Biological Process	GO:0010506	regulation of autophagy	IBA	J:265628
Biological Process	GO:0001558	regulation of cell growth	ISO	J:164563
Biological Process	GO:0008361	regulation of cell size	ISO	J:164563
Biological Process	GO:0042325	regulation of phosphorylation	ISO	J:155856
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:219062
Biological Process	GO:0009410	response to xenobiotic stimulus	IMP	J:302579
Biological Process	GO:0035176	social behavior	IMP	J:302579
Biological Process	GO:0031929	TOR signaling	ISO	J:164563
Biological Process	GO:0038202	TORC1 signaling	ISO	J:164563
Biological Process	GO:0038202	TORC1 signaling	IBA	J:265628