GO Annotations Graph

• Symbol: Ddit4
• Name: DNA-damage-inducible transcript 4
• ID: MGI:1921997

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	IBA	J:265628
Molecular Function	GO:0071889	14-3-3 protein binding	IDA	J:131386
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:158772
Biological Process	GO:0006915	apoptotic process	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	IBA	J:265628
Biological Process	GO:0007420	brain development	ISO	J:155856
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	IDA	J:141655
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP	J:178326
Biological Process	GO:0045820	negative regulation of glycolytic process	IMP	J:158772
Biological Process	GO:1902532	negative regulation of intracellular signal transduction	ISO	J:155856
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	ISO	J:155856
Biological Process	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	ISO	J:155856
Biological Process	GO:0009968	negative regulation of signal transduction	IEA	J:72247
Biological Process	GO:0032007	negative regulation of TOR signaling	ISO	J:164563
Biological Process	GO:0032007	negative regulation of TOR signaling	ISO	J:155856
Biological Process	GO:0032007	negative regulation of TOR signaling	IBA	J:265628
Biological Process	GO:0032007	negative regulation of TOR signaling	IMP	J:131386
Biological Process	GO:0030182	neuron differentiation	ISO	J:155856
Biological Process	GO:0001764	neuron migration	ISO	J:155856
Biological Process	GO:0048011	neurotrophin TRK receptor signaling pathway	ISO	J:155856
Biological Process	GO:1901216	positive regulation of neuron death	ISO	J:155856
Biological Process	GO:0032984	protein-containing complex disassembly	IMP	J:131386
Biological Process	GO:0072593	reactive oxygen species metabolic process	IMP	J:158772
Biological Process	GO:0001666	response to hypoxia	ISO	J:164563
Biological Process	GO:0001666	response to hypoxia	ISO	J:155856
Biological Process	GO:0001666	response to hypoxia	IBA	J:265628
Biological Process	GO:0001666	response to hypoxia	IMP	J:131386