GO Annotations Graph

• Symbol: Tpr
• Name: translocated promoter region, nuclear basket protein
• ID: MGI:1922066

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0070840	dynein complex binding	ISO	J:164563
Molecular Function	GO:0031072	heat shock protein binding	ISO	J:164563
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	ISO	J:164563
Molecular Function	GO:0003729	mRNA binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:196277
Molecular Function	GO:0005515	protein binding	IPI	J:233663
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0017056	structural constituent of nuclear pore	ISO	J:164563
Molecular Function	GO:0017056	structural constituent of nuclear pore	IBA	J:265628
Molecular Function	GO:0015631	tubulin binding	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005868	cytoplasmic dynein complex	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0019898	extrinsic component of membrane	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0005635	nuclear envelope	IDA	J:196277
Cellular Component	GO:0005635	nuclear envelope	IDA	J:81719
Cellular Component	GO:0042405	nuclear inclusion body	ISO	J:155856
Cellular Component	GO:0042405	nuclear inclusion body	IDA	J:196277
Cellular Component	GO:0042405	nuclear inclusion body	ISO	J:164563
Cellular Component	GO:0031965	nuclear membrane	ISO	J:155856
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0034399	nuclear periphery	ISO	J:155856
Cellular Component	GO:0034399	nuclear periphery	ISO	J:164563
Cellular Component	GO:0034399	nuclear periphery	IDA	J:196240
Cellular Component	GO:0005643	nuclear pore	ISO	J:164563
Cellular Component	GO:0005643	nuclear pore	NAS	J:320054
Cellular Component	GO:0005643	nuclear pore	IDA	J:196277
Cellular Component	GO:0005643	nuclear pore	IBA	J:265628
Cellular Component	GO:0044615	nuclear pore nuclear basket	ISO	J:155856
Cellular Component	GO:0044615	nuclear pore nuclear basket	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0034605	cellular response to heat	ISO	J:164563
Biological Process	GO:0035457	cellular response to interferon-alpha	IDA	J:196277
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	ISO	J:164563
Biological Process	GO:0006406	mRNA export from nucleus	IBA	J:265628
Biological Process	GO:0031990	mRNA export from nucleus in response to heat stress	ISO	J:164563
Biological Process	GO:0051028	mRNA transport	IEA	J:60000
Biological Process	GO:0046832	negative regulation of RNA export from nucleus	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045947	negative regulation of translational initiation	ISO	J:164563
Biological Process	GO:0006913	nucleocytoplasmic transport	NAS	J:320054
Biological Process	GO:0031453	positive regulation of heterochromatin formation	ISO	J:164563
Biological Process	GO:0090316	positive regulation of intracellular protein transport	ISO	J:164563
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	ISO	J:164563
Biological Process	GO:0046827	positive regulation of protein export from nucleus	ISO	J:155856
Biological Process	GO:0042307	positive regulation of protein import into nucleus	ISO	J:164563
Biological Process	GO:0006611	protein export from nucleus	ISO	J:155856
Biological Process	GO:0006606	protein import into nucleus	IEA	J:72247
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0010965	regulation of mitotic sister chromatid separation	ISO	J:164563
Biological Process	GO:1901673	regulation of mitotic spindle assembly	ISO	J:164563
Biological Process	GO:0032880	regulation of protein localization	ISO	J:164563
Biological Process	GO:0070849	response to epidermal growth factor	ISO	J:164563
Biological Process	GO:0006405	RNA export from nucleus	ISO	J:164563
Biological Process	GO:0006404	RNA import into nucleus	ISO	J:164563