GO Annotations Graph

• Symbol: Dusp18
• Name: dual specificity phosphatase 18
• ID: MGI:1922469

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	IEA	J:72247
Molecular Function	GO:0017018	myosin phosphatase activity	IEA	J:72245
Molecular Function	GO:0016791	phosphatase activity	ISO	J:164563
Molecular Function	GO:0016791	phosphatase activity	ISS	J:137567
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:60000
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	IEA	J:72245
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ISO	J:164563
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IBA	J:265628
Molecular Function	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISS	J:137567
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0031314	extrinsic component of mitochondrial inner membrane	ISS	J:137567
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	ISS	J:137567
Cellular Component	GO:0005758	mitochondrial intermembrane space	ISO	J:155856
Cellular Component	GO:0005758	mitochondrial intermembrane space	ISS	J:137567
Cellular Component	GO:0005739	mitochondrion	ISS	J:137567
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0016311	dephosphorylation	ISO	J:164563
Biological Process	GO:0035970	peptidyl-threonine dephosphorylation	ISO	J:164563
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	ISO	J:164563
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	IBA	J:265628
Biological Process	GO:0006470	protein dephosphorylation	IEA	J:72247
Biological Process	GO:0033365	protein localization to organelle	ISS	J:137567
Biological Process	GO:0006612	protein targeting to membrane	ISS	J:137567
Biological Process	GO:0006626	protein targeting to mitochondrion	ISS	J:137567
Biological Process	GO:0046677	response to antibiotic	ISS	J:137567