GO Annotations Graph

• Symbol: Nhej1
• Name: non-homologous end joining factor 1
• ID: MGI:1922820

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0045027	DNA end binding	ISO	J:164563
Molecular Function	GO:0045027	DNA end binding	IBA	J:265628
Molecular Function	GO:0070182	DNA polymerase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:265834
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0032807	DNA ligase IV complex	IBA	J:265628
Cellular Component	GO:0001650	fibrillar center	ISO	J:164563
Cellular Component	GO:0070419	nonhomologous end joining complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISS	J:116419
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISS	J:116418
Cellular Component	GO:0035861	site of double-strand break	ISO	J:164563
Biological Process	GO:0030183	B cell differentiation	ISO	J:164563
Biological Process	GO:0030183	B cell differentiation	ISS	J:116419
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0051103	DNA ligation involved in DNA repair	ISO	J:164563
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0006302	double-strand break repair	IEA	J:72247
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	ISS	J:116419
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	IMP	J:236776
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	ISO	J:164563
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	ISS	J:116418
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	IMP	J:238544
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	IBA	J:265628
Biological Process	GO:0033152	immunoglobulin V(D)J recombination	ISO	J:164563
Biological Process	GO:0010212	response to ionizing radiation	ISO	J:164563
Biological Process	GO:0010212	response to ionizing radiation	ISS	J:116418
Biological Process	GO:0030217	T cell differentiation	ISS	J:116419
Biological Process	GO:0030217	T cell differentiation	ISO	J:164563