GO Annotations Graph

• Symbol: Pik3r4
• Name: phosphoinositide-3-kinase regulatory subunit 4
• ID: MGI:1922919

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:245272
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005930	axoneme	IDA	J:203423
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005770	late endosome	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0015630	microtubule cytoskeleton	ISO	J:164563
Cellular Component	GO:0071561	nucleus-vacuole junction	IBA	J:265628
Cellular Component	GO:0035032	phosphatidylinositol 3-kinase complex, class III	IDA	J:219056
Cellular Component	GO:0035032	phosphatidylinositol 3-kinase complex, class III	ISO	J:164563
Cellular Component	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	IBA	J:265628
Cellular Component	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	IBA	J:265628
Biological Process	GO:0097352	autophagosome maturation	ISO	J:164563
Biological Process	GO:0030242	autophagy of peroxisome	IBA	J:265628
Biological Process	GO:0042149	cellular response to glucose starvation	IDA	J:219056
Biological Process	GO:0045022	early endosome to late endosome transport	ISO	J:164563
Biological Process	GO:0045324	late endosome to vacuole transport	IBA	J:265628
Biological Process	GO:0016236	macroautophagy	IBA	J:265628
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IBA	J:265628
Biological Process	GO:0006622	protein targeting to lysosome	NAS	J:106494
Biological Process	GO:0006623	protein targeting to vacuole	IBA	J:265628
Biological Process	GO:0032801	receptor catabolic process	ISO	J:164563
Biological Process	GO:0010506	regulation of autophagy	ISO	J:164563
Biological Process	GO:0032465	regulation of cytokinesis	ISO	J:164563
Biological Process	GO:0016241	regulation of macroautophagy	ISO	J:164563