GO Annotations Graph

• Symbol: Shld2
• Name: shieldin complex subunit 2
• ID: MGI:1922948

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0000785	chromatin	NAS	J:261998
Cellular Component	GO:0005694	chromosome	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0035861	site of double-strand break	ISO	J:164563
Cellular Component	GO:0035861	site of double-strand break	NAS	J:261998
Cellular Component	GO:0035861	site of double-strand break	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	NAS	J:261998
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	ISO	J:164563
Biological Process	GO:0045830	positive regulation of isotype switching	ISO	J:164563
Biological Process	GO:0010569	regulation of double-strand break repair via homologous recombination	IBA	J:265628
Biological Process	GO:0002208	somatic diversification of immunoglobulins involved in immune response	NAS	J:261998
Biological Process	GO:0043247	telomere maintenance in response to DNA damage	NAS	J:261998