GO Annotations Graph

• Symbol: Tbx18
• Name: T-box18
• ID: MGI:1923615

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:124772
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:124772
Molecular Function	GO:0005515	protein binding	IPI	J:157941
Molecular Function	GO:0005515	protein binding	IPI	J:124772
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:124772
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:124772
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:124772
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:124772
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:124772
Cellular Component	GO:0090571	RNA polymerase II transcription repressor complex	IDA	J:124772
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IMP	J:153783
Biological Process	GO:0009948	anterior/posterior axis specification	IMP	J:90513
Biological Process	GO:0030154	cell differentiation	IMP	J:134489
Biological Process	GO:0001708	cell fate specification	IBA	J:265628
Biological Process	GO:0090103	cochlea morphogenesis	IMP	J:134489
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:106499
Biological Process	GO:0010463	mesenchymal cell proliferation	IMP	J:106499
Biological Process	GO:0072198	mesenchymal cell proliferation involved in ureter development	IGI	J:157941
Biological Process	GO:0072198	mesenchymal cell proliferation involved in ureter development	IGI	J:157941
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	IBA	J:265628
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	IMP	J:106499
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0051450	myoblast proliferation	IGI	J:157941
Biological Process	GO:0060829	negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	IDA	J:124772
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:124772
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	IMP	J:134489
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IMP	J:106499
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IMP	J:106499
Biological Process	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	IGI	J:157941
Biological Process	GO:2000288	positive regulation of myoblast proliferation	IGI	J:157941
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IMP	J:106499
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0098907	regulation of SA node cell action potential	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0007605	sensory perception of sound	IMP	J:134489
Biological Process	GO:0060931	sinoatrial node cell development	ISO	J:164563
Biological Process	GO:0060930	sinoatrial node cell fate commitment	ISO	J:164563
Biological Process	GO:0003163	sinoatrial node development	IMP	J:153783
Biological Process	GO:0051145	smooth muscle cell differentiation	IMP	J:106499
Biological Process	GO:0001756	somitogenesis	IBA	J:265628
Biological Process	GO:0001756	somitogenesis	IMP	J:90513
Biological Process	GO:0048863	stem cell differentiation	IMP	J:134489
Biological Process	GO:0072089	stem cell proliferation	IMP	J:106499
Biological Process	GO:0072189	ureter development	ISO	J:164563
Biological Process	GO:0072189	ureter development	IGI	J:166547