Arpc2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Arpc2
actin related protein 2/3 complex, subunit 2
MGI:1923959

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0051117	ATPase binding	ISO	J:155856
Molecular Function	GO:0035254	glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:141431
Molecular Function	GO:0005515	protein binding	IPI	J:141431
Molecular Function	GO:0005515	protein binding	IPI	J:197772
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0005200	structural constituent of cytoskeleton	ISO	J:164563
Molecular Function	GO:0005200	structural constituent of cytoskeleton	IBA	J:265628
Cellular Component	GO:0015629	actin cytoskeleton	IEA	J:72247
Cellular Component	GO:0061834	actin filament branch point	ISO	J:155856
Cellular Component	GO:0097440	apical dendrite	ISO	J:155856
Cellular Component	GO:0005885	Arp2/3 protein complex	ISO	J:164563
Cellular Component	GO:0005885	Arp2/3 protein complex	IBA	J:265628
Cellular Component	GO:0005885	Arp2/3 protein complex	TAS	J:80756
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0031252	cell leading edge	ISO	J:155856
Cellular Component	GO:0031252	cell leading edge	IDA	J:141431
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0061830	concave side of sperm head	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0005768	endosome	IDA	J:185589
Cellular Component	GO:0031941	filamentous actin	ISO	J:155856
Cellular Component	GO:0005925	focal adhesion	IDA	J:80756
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:206458
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:206458
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0036195	muscle cell projection membrane	IDA	J:197772
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0090725	peripheral region of growth cone	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:185589
Cellular Component	GO:0061825	podosome core	ISO	J:155856
Cellular Component	GO:0061826	podosome ring	ISO	J:155856
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0032587	ruffle membrane	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	ISO	J:155856
Cellular Component	GO:0030141	secretory granule	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:206458
Cellular Component	GO:0045202	synapse	EXP	J:206458
Cellular Component	GO:0061835	ventral surface of cell	ISO	J:155856
Biological Process	GO:0030041	actin filament polymerization	IEA	J:72247
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	ISO	J:164563
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	IBA	J:265628
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ISO	J:155856
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	ISO	J:155856
Biological Process	GO:0072752	cellular response to rapamycin	ISO	J:155856
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	ISO	J:155856
Biological Process	GO:0030838	positive regulation of actin filament polymerization	IDA	J:141431
Biological Process	GO:2000814	positive regulation of barbed-end actin filament capping	ISO	J:155856
Biological Process	GO:0051491	positive regulation of filopodium assembly	ISO	J:155856
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:164563
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:155856
Biological Process	GO:0071803	positive regulation of podosome assembly	ISO	J:155856
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	ISO	J:155856
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	ISO	J:155856
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	IMP	J:185589
Biological Process	GO:0070528	protein kinase C signaling	ISO	J:155856
Biological Process	GO:0030833	regulation of actin filament polymerization	IEA	J:72247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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