GO Annotations Graph

• Symbol: Kdm4c
• Name: lysine (K)-specific demethylase 4C
• ID: MGI:1924054

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051213	dioxygenase activity	IEA	J:60000
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	IPI	J:169894
Molecular Function	GO:0032452	histone demethylase activity	ISO	J:164563
Molecular Function	GO:0032452	histone demethylase activity	IDA	J:148615
Molecular Function	GO:0051864	histone H3K36 demethylase activity	ISO	J:164563
Molecular Function	GO:0051864	histone H3K36 demethylase activity	IBA	J:265628
Molecular Function	GO:0032454	histone H3K9 demethylase activity	ISO	J:164563
Molecular Function	GO:0032454	histone H3K9 demethylase activity	IBA	J:265628
Molecular Function	GO:0032454	histone H3K9 demethylase activity	IDA	J:109728
Molecular Function	GO:0032454	histone H3K9 demethylase activity	IMP	J:125698
Molecular Function	GO:0140684	histone H3K9me2/H3K9me3 demethylase activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0050681	nuclear androgen receptor binding	ISO	J:164563
Molecular Function	GO:0050681	nuclear androgen receptor binding	IPI	J:169894
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005721	pericentric heterochromatin	IDA	J:109728
Biological Process	GO:0001825	blastocyst formation	IMP	J:156652
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	IBA	J:265628
Biological Process	GO:0033169	histone H3-K9 demethylation	ISO	J:164563
Biological Process	GO:0016570	histone modification	IDA	J:148615
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	IMP	J:125698
Biological Process	GO:0010468	regulation of gene expression	IMP	J:156652
Biological Process	GO:2000736	regulation of stem cell differentiation	IDA	J:125698
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0019827	stem cell population maintenance	IGI	J:125698