GO Annotations Graph

• Symbol: Ago4
• Name: argonaute RISC catalytic subunit 4
• ID: MGI:1924100

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003725	double-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0035198	miRNA binding	ISO	J:164563
Molecular Function	GO:0035198	miRNA binding	IBA	J:265628
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0003723	RNA binding	IDA	J:150716
Molecular Function	GO:0004521	RNA endonuclease activity	IBA	J:265628
Molecular Function	GO:0003727	single-stranded RNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:187588
Cellular Component	GO:0000932	P-body	IDA	J:158290
Cellular Component	GO:0016442	RISC complex	ISO	J:164563
Cellular Component	GO:0016442	RISC complex	IDA	J:150716
Cellular Component	GO:0070578	RISC-loading complex	ISO	J:164563
Biological Process	GO:0008584	male gonad development	IMP	J:187588
Biological Process	GO:0007140	male meiotic nuclear division	IMP	J:187588
Biological Process	GO:0010586	miRNA metabolic process	IMP	J:187588
Biological Process	GO:0035196	miRNA processing	ISO	J:164563
Biological Process	GO:0035278	miRNA-mediated gene silencing by inhibition of translation	ISO	J:164563
Biological Process	GO:0006402	mRNA catabolic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:187588
Biological Process	GO:0031054	pre-miRNA processing	ISO	J:164563
Biological Process	GO:0022604	regulation of cell morphogenesis	IMP	J:187588
Biological Process	GO:0006417	regulation of translation	IEA	J:60000
Biological Process	GO:0070922	RISC complex assembly	ISO	J:164563
Biological Process	GO:0010501	RNA secondary structure unwinding	ISO	J:164563
Biological Process	GO:0031047	RNA-mediated gene silencing	IEA	J:60000
Biological Process	GO:0007130	synaptonemal complex assembly	IMP	J:187588