GO Annotations Graph

• Symbol: Cyfip2
• Name: cytoplasmic FMR1 interacting protein 2
• ID: MGI:1924134

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:88664
Molecular Function	GO:0005515	protein binding	IPI	J:249721
Molecular Function	GO:0005515	protein binding	IPI	J:239183
Molecular Function	GO:0031267	small GTPase binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:88664
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0031209	SCAR complex	ISO	J:164563
Cellular Component	GO:0031209	SCAR complex	IDA	J:302461
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0045202	synapse	ISO	J:88664
Cellular Component	GO:0045202	synapse	IEP	J:88664
Cellular Component	GO:0045202	synapse	IDA	J:88664
Cellular Component	GO:0045202	synapse	IDA	J:88664
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	ISO	J:164563
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0000902	cell morphogenesis	IBA	J:265628
Biological Process	GO:0030031	cell projection assembly	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	ISO	J:164563
Biological Process	GO:0097484	dendrite extension	IMP	J:239183
Biological Process	GO:0031175	neuron projection development	IMP	J:239183
Biological Process	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway	IMP	J:239183
Biological Process	GO:0045862	positive regulation of proteolysis	ISO	J:164563
Biological Process	GO:0030833	regulation of actin filament polymerization	IEA	J:72247