GO Annotations Graph

• Symbol: Lrg1
• Name: leucine-rich alpha-2-glycoprotein 1
• ID: MGI:1924155

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0099104	potassium channel activator activity	IBA	J:265628
Molecular Function	GO:0005160	transforming growth factor beta receptor binding	IPI	J:204744
Molecular Function	GO:0005160	transforming growth factor beta receptor binding	IPI	J:204744
Molecular Function	GO:0005160	transforming growth factor beta receptor binding	IPI	J:204744
Molecular Function	GO:0044325	transmembrane transporter binding	IBA	J:265628
Molecular Function	GO:0034713	type I transforming growth factor beta receptor binding	ISO	J:164563
Molecular Function	GO:0005114	type II transforming growth factor beta receptor binding	ISO	J:164563
Molecular Function	GO:0005249	voltage-gated potassium channel activity	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:204744
Cellular Component	GO:0005615	extracellular space	ISO	J:73065
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IBA	J:265628
Biological Process	GO:0050873	brown fat cell differentiation	IDA	J:137608
Biological Process	GO:0051546	keratinocyte migration	IMP	J:298977
Biological Process	GO:0051546	keratinocyte migration	ISO	J:164563
Biological Process	GO:0061756	leukocyte adhesion to vascular endothelial cell	IMP	J:298977
Biological Process	GO:0061756	leukocyte adhesion to vascular endothelial cell	ISO	J:164563
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0045766	positive regulation of angiogenesis	IDA	J:204744
Biological Process	GO:0045766	positive regulation of angiogenesis	IMP	J:204744
Biological Process	GO:0045766	positive regulation of angiogenesis	IGI	J:204744
Biological Process	GO:0045766	positive regulation of angiogenesis	IGI	J:204744
Biological Process	GO:0045766	positive regulation of angiogenesis	IGI	J:204744
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	IMP	J:204744
Biological Process	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	ISO	J:164563
Biological Process	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	IMP	J:298977
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0010838	positive regulation of keratinocyte proliferation	IMP	J:298977
Biological Process	GO:0010838	positive regulation of keratinocyte proliferation	ISO	J:164563
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	IGI	J:204744
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0035313	wound healing, spreading of epidermal cells	IMP	J:298977
Biological Process	GO:0035313	wound healing, spreading of epidermal cells	ISO	J:164563