Mtmr2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Mtmr2
myotubularin related protein 2
MGI:1924366

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	IPI	J:106780
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0052866	phosphatidylinositol phosphate phosphatase activity	IMP	J:177998
Molecular Function	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	ISO	J:164563
Molecular Function	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	IBA	J:265628
Molecular Function	GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:106780
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:84578
Cellular Component	GO:0005737	cytoplasm	IDA	J:106780
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6809875
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6809916
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6809945
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6809977
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-6810026
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0097060	synaptic membrane	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0005774	vacuolar membrane	IDA	J:106780
Biological Process	GO:0097062	dendritic spine maintenance	ISO	J:155856
Biological Process	GO:0016311	dephosphorylation	IDA	J:106780
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0032288	myelin assembly	IGI	J:177998
Biological Process	GO:0032288	myelin assembly	IMP	J:177998
Biological Process	GO:0032288	myelin assembly	IGI	J:177998
Biological Process	GO:0032288	myelin assembly	IMP	J:177998
Biological Process	GO:0032288	myelin assembly	IGI	J:177998
Biological Process	GO:0042552	myelination	IGI	J:177998
Biological Process	GO:0045806	negative regulation of endocytosis	ISO	J:155856
Biological Process	GO:0090394	negative regulation of excitatory postsynaptic potential	ISO	J:155856
Biological Process	GO:0031642	negative regulation of myelination	IMP	J:151079
Biological Process	GO:0031642	negative regulation of myelination	IGI	J:177998
Biological Process	GO:2000645	negative regulation of receptor catabolic process	ISO	J:155856
Biological Process	GO:0002091	negative regulation of receptor internalization	ISO	J:155856
Biological Process	GO:0048666	neuron development	IGI	J:177998
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	ISO	J:164563
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	IDA	J:106780
Biological Process	GO:0046488	phosphatidylinositol metabolic process	IMP	J:177998
Biological Process	GO:0046488	phosphatidylinositol metabolic process	IMP	J:177998
Biological Process	GO:2000643	positive regulation of early endosome to late endosome transport	ISO	J:155856
Biological Process	GO:0060304	regulation of phosphatidylinositol dephosphorylation	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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