GO Annotations Graph

• Symbol: Prdm8
• Name: PR domain containing 8
• ID: MGI:1924880

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:182304
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	IDA	J:152723
Molecular Function	GO:0042054	histone methyltransferase activity	IDA	J:152723
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:182304
Molecular Function	GO:0003714	transcription corepressor activity	IMP	J:182304
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0035097	histone methyltransferase complex	IC	J:152723
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:152723
Cellular Component	GO:0005634	nucleus	IDA	J:182304
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	IMP	J:182304
Biological Process	GO:0021540	corpus callosum morphogenesis	IMP	J:182304
Biological Process	GO:0021957	corticospinal tract morphogenesis	IMP	J:182304
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:152723
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:182304
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0022008	neurogenesis	IDA	J:144373
Biological Process	GO:0014003	oligodendrocyte development	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	IBA	J:265628