GO Annotations Graph

• Symbol: Ccdc88a
• Name: coiled coil domain containing 88A
• ID: MGI:1925177

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0051959	dynein light intermediate chain binding	IBA	J:265628
Molecular Function	GO:0005154	epidermal growth factor receptor binding	ISO	J:164563
Molecular Function	GO:0001965	G-protein alpha-subunit binding	ISO	J:164563
Molecular Function	GO:0031682	G-protein gamma-subunit binding	ISO	J:155856
Molecular Function	GO:0005092	GDP-dissociation inhibitor activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005158	insulin receptor binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	IDA	J:121601
Molecular Function	GO:0008017	microtubule binding	IBA	J:265628
Molecular Function	GO:0035091	phosphatidylinositol binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:154919
Molecular Function	GO:0005515	protein binding	IPI	J:211500
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0043422	protein kinase B binding	IPI	J:99088
Molecular Function	GO:0043422	protein kinase B binding	ISO	J:164563
Molecular Function	GO:0005080	protein kinase C binding	ISO	J:164563
Molecular Function	GO:0042169	SH2 domain binding	ISO	J:164563
Molecular Function	GO:0043184	vascular endothelial growth factor receptor 2 binding	ISO	J:164563
Cellular Component	GO:0031252	cell leading edge	IDA	J:211500
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005814	centriole	ISO	J:164563
Cellular Component	GO:0005813	centrosome	IBA	J:265628
Cellular Component	GO:0036064	ciliary basal body	ISO	J:164563
Cellular Component	GO:0030142	COPI-coated Golgi to ER transport vesicle	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0032147	activation of protein kinase activity	ISO	J:164563
Biological Process	GO:0032148	activation of protein kinase B activity	IDA	J:99088
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0030030	cell projection organization	IEA	J:60000
Biological Process	GO:0031122	cytoplasmic microtubule organization	IBA	J:265628
Biological Process	GO:0030705	cytoskeleton-dependent intracellular transport	IBA	J:265628
Biological Process	GO:0006260	DNA replication	IEA	J:60000
Biological Process	GO:0030032	lamellipodium assembly	ISO	J:164563
Biological Process	GO:0072660	maintenance of protein location in plasma membrane	ISO	J:164563
Biological Process	GO:0061024	membrane organization	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0045724	positive regulation of cilium assembly	ISO	J:164563
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:1903566	positive regulation of protein localization to cilium	ISO	J:164563
Biological Process	GO:0051496	positive regulation of stress fiber assembly	ISO	J:164563
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:99088
Biological Process	GO:0006275	regulation of DNA replication	IMP	J:99088
Biological Process	GO:0010975	regulation of neuron projection development	IDA	J:154919
Biological Process	GO:0001932	regulation of protein phosphorylation	IDA	J:99088
Biological Process	GO:0007264	small GTPase mediated signal transduction	ISO	J:164563
Biological Process	GO:0031929	TOR signaling	IDA	J:154919