GO Annotations Graph

• Symbol: Scaf8
• Name: SR-related CTD-associated factor 8
• ID: MGI:1925212

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003729	mRNA binding	IBA	J:265628
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0070063	RNA polymerase binding	ISO	J:155856
Molecular Function	GO:0043175	RNA polymerase core enzyme binding	ISO	J:164563
Molecular Function	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding	ISO	J:164563
Molecular Function	GO:0000993	RNA polymerase II complex binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005849	mRNA cleavage factor complex	IBA	J:265628
Cellular Component	GO:0016363	nuclear matrix	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0006378	mRNA polyadenylation	IBA	J:265628
Biological Process	GO:0006397	mRNA processing	ISO	J:155856
Biological Process	GO:2000805	negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled	ISO	J:164563
Biological Process	GO:0032786	positive regulation of DNA-templated transcription, elongation	ISO	J:164563
Biological Process	GO:0006369	termination of RNA polymerase II transcription	IBA	J:265628
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:155856