GO Annotations Graph

• Symbol: Adgra2
• Name: adhesion G protein-coupled receptor A2
• ID: MGI:1925810

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	IDA	J:171226
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	IDA	J:256044
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:71592
Cellular Component	GO:1990909	Wnt signalosome	ISO	J:164563
Cellular Component	GO:1990909	Wnt signalosome	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IMP	J:171226
Biological Process	GO:0007166	cell surface receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007417	central nervous system development	IMP	J:166127
Biological Process	GO:0007417	central nervous system development	IBA	J:265628
Biological Process	GO:0043542	endothelial cell migration	IMP	J:166127
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway	IMP	J:171226
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IDA	J:256044
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0010595	positive regulation of endothelial cell migration	IDA	J:171226
Biological Process	GO:0045765	regulation of angiogenesis	IMP	J:166127
Biological Process	GO:0050920	regulation of chemotaxis	IMP	J:166127
Biological Process	GO:0090210	regulation of establishment of blood-brain barrier	IMP	J:251212
Biological Process	GO:0090210	regulation of establishment of blood-brain barrier	IMP	J:171226
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0002040	sprouting angiogenesis	IMP	J:166127
Biological Process	GO:0002040	sprouting angiogenesis	IBA	J:265628
Biological Process	GO:0002040	sprouting angiogenesis	IMP	J:200671
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000