GO Annotations Graph

• Symbol: Rictor
• Name: RPTOR independent companion of MTOR, complex 2
• ID: MGI:1926007

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:182033
Molecular Function	GO:0005515	protein binding	IPI	J:137614
Molecular Function	GO:0005515	protein binding	IPI	J:232620
Molecular Function	GO:0005515	protein binding	IPI	J:139950
Molecular Function	GO:0005515	protein binding	IPI	J:164024
Molecular Function	GO:0005515	protein binding	IPI	J:167176
Molecular Function	GO:0005515	protein binding	IPI	J:167176
Molecular Function	GO:0005515	protein binding	IPI	J:172256
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	ISO	J:164563
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	IBA	J:265628
Molecular Function	GO:0043022	ribosome binding	IDA	J:167176
Cellular Component	GO:0031932	TORC2 complex	ISO	J:164563
Cellular Component	GO:0031932	TORC2 complex	IDA	J:125618
Cellular Component	GO:0031932	TORC2 complex	IBA	J:265628
Biological Process	GO:0031532	actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0031669	cellular response to nutrient levels	NAS	J:319697
Biological Process	GO:0007010	cytoskeleton organization	NAS	J:320275
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	IMP	J:119564
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	NAS	J:319697
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	ISO	J:164563
Biological Process	GO:0030838	positive regulation of actin filament polymerization	IMP	J:93907
Biological Process	GO:0030307	positive regulation of cell growth	NAS	J:319697
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:155856
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IMP	J:93907
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:155856
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	IBA	J:265628
Biological Process	GO:0032008	positive regulation of TOR signaling	ISO	J:164563
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:2000114	regulation of establishment of cell polarity	IMP	J:215205
Biological Process	GO:0010468	regulation of gene expression	IMP	J:215205
Biological Process	GO:0043087	regulation of GTPase activity	IMP	J:93907
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:215205
Biological Process	GO:0033135	regulation of peptidyl-serine phosphorylation	IMP	J:215205
Biological Process	GO:0042325	regulation of phosphorylation	ISO	J:155856
Biological Process	GO:0051896	regulation of protein kinase B signaling	IDA	J:119564
Biological Process	GO:0051896	regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:219062
Biological Process	GO:0031929	TOR signaling	IEA	J:72247
Biological Process	GO:0038203	TORC2 signaling	ISO	J:164563
Biological Process	GO:0038203	TORC2 signaling	IBA	J:265628