GO Annotations Graph

• Symbol: Nckap1l
• Name: NCK associated protein 1 like
• ID: MGI:1926063

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:164563
Molecular Function	GO:0030295	protein kinase activator activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:1904841	TORC2 complex binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0031209	SCAR complex	ISO	J:164563
Cellular Component	GO:0031209	SCAR complex	IMP	J:141377
Cellular Component	GO:0031209	SCAR complex	IBA	J:265628
Biological Process	GO:0070358	actin polymerization-dependent cell motility	ISO	J:164563
Biological Process	GO:0001782	B cell homeostasis	IMP	J:141377
Biological Process	GO:0050853	B cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0000902	cell morphogenesis	IBA	J:265628
Biological Process	GO:0030031	cell projection assembly	IBA	J:265628
Biological Process	GO:0006935	chemotaxis	ISO	J:164563
Biological Process	GO:0030866	cortical actin cytoskeleton organization	IMP	J:199414
Biological Process	GO:0030866	cortical actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0030866	cortical actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0034101	erythrocyte homeostasis	IMP	J:199414
Biological Process	GO:0030011	maintenance of cell polarity	ISO	J:164563
Biological Process	GO:0002262	myeloid cell homeostasis	IMP	J:141377
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043318	negative regulation of cytotoxic T cell degranulation	ISO	J:164563
Biological Process	GO:0032700	negative regulation of interleukin-17 production	IMP	J:141377
Biological Process	GO:0032715	negative regulation of interleukin-6 production	IMP	J:141377
Biological Process	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity	ISO	J:164563
Biological Process	GO:0048812	neuron projection morphogenesis	IBA	J:265628
Biological Process	GO:0030593	neutrophil chemotaxis	ISO	J:164563
Biological Process	GO:0030838	positive regulation of actin filament polymerization	ISO	J:164563
Biological Process	GO:0030838	positive regulation of actin filament polymerization	IMP	J:141377
Biological Process	GO:0045579	positive regulation of B cell differentiation	IMP	J:141377
Biological Process	GO:0030890	positive regulation of B cell proliferation	ISO	J:164563
Biological Process	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	IMP	J:141377
Biological Process	GO:0043378	positive regulation of CD8-positive, alpha-beta T cell differentiation	IMP	J:141377
Biological Process	GO:0033630	positive regulation of cell adhesion mediated by integrin	IMP	J:141377
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	IMP	J:141377
Biological Process	GO:0045588	positive regulation of gamma-delta T cell differentiation	IMP	J:141377
Biological Process	GO:0002687	positive regulation of leukocyte migration	ISO	J:164563
Biological Process	GO:0045621	positive regulation of lymphocyte differentiation	IMP	J:141377
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	IMP	J:141377
Biological Process	GO:1902624	positive regulation of neutrophil migration	ISO	J:164563
Biological Process	GO:0060100	positive regulation of phagocytosis, engulfment	IMP	J:141377
Biological Process	GO:0042327	positive regulation of phosphorylation	ISO	J:164563
Biological Process	GO:0042102	positive regulation of T cell proliferation	IMP	J:141377
Biological Process	GO:0042102	positive regulation of T cell proliferation	ISO	J:164563
Biological Process	GO:1904515	positive regulation of TORC2 signaling	ISO	J:164563
Biological Process	GO:0065003	protein-containing complex assembly	IMP	J:141377
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:164563
Biological Process	GO:0043029	T cell homeostasis	IMP	J:141377