GO Annotations Graph

• Symbol: Slc25a12
• Name: solute carrier family 25 (mitochondrial carrier, Aralar), member 12
• ID: MGI:1926080

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000514	3-sulfino-L-alanine: proton, glutamate antiporter activity	ISO	J:164563
Molecular Function	GO:0015172	acidic amino acid transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015172	acidic amino acid transmembrane transporter activity	IMP	J:101164
Molecular Function	GO:0000515	aspartate:glutamate, proton antiporter activity	ISO	J:164563
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0015183	L-aspartate transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:164563
Cellular Component	GO:0005743	mitochondrial inner membrane	IMP	J:101164
Cellular Component	GO:0005743	mitochondrial inner membrane	HDA	J:100953
Cellular Component	GO:0005743	mitochondrial inner membrane	TAS	J:87578
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	IDA	J:87578
Cellular Component	GO:0005739	mitochondrion	IMP	J:120897
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Biological Process	GO:0015810	aspartate transmembrane transport	ISO	J:164563
Biological Process	GO:0015810	aspartate transmembrane transport	IBA	J:265628
Biological Process	GO:0006537	glutamate biosynthetic process	ISO	J:155856
Biological Process	GO:0015813	L-glutamate transmembrane transport	ISO	J:164563
Biological Process	GO:0015813	L-glutamate transmembrane transport	IBA	J:265628
Biological Process	GO:0043490	malate-aspartate shuttle	ISO	J:155856
Biological Process	GO:0043490	malate-aspartate shuttle	ISO	J:164563
Biological Process	GO:0043490	malate-aspartate shuttle	IBA	J:265628
Biological Process	GO:0043490	malate-aspartate shuttle	IMP	J:120897
Biological Process	GO:1904024	negative regulation of glucose catabolic process to lactate via pyruvate	ISO	J:155856
Biological Process	GO:2001171	positive regulation of ATP biosynthetic process	ISO	J:155856
Biological Process	GO:0010907	positive regulation of glucose metabolic process	ISO	J:155856
Biological Process	GO:0031643	positive regulation of myelination	ISO	J:155856
Biological Process	GO:0051592	response to calcium ion	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247