GO Annotations Graph

• Symbol: Emilin1
• Name: elastin microfibril interfacer 1
• ID: MGI:1926189

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030023	extracellular matrix constituent conferring elasticity	RCA	J:265604
Molecular Function	GO:0030023	extracellular matrix constituent conferring elasticity	RCA	J:265607
Molecular Function	GO:0030023	extracellular matrix constituent conferring elasticity	IBA	J:265628
Molecular Function	GO:0030023	extracellular matrix constituent conferring elasticity	IMP	J:87574
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IDA	J:87574
Molecular Function	GO:0098640	integrin binding involved in cell-matrix adhesion	ISO	J:164563
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:297323
Molecular Function	GO:0005515	protein binding	IPI	J:115889
Cellular Component	GO:0005581	collagen trimer	IEA	J:60000
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:213088
Cellular Component	GO:0062023	collagen-containing extracellular matrix	NAS	J:320284
Cellular Component	GO:1990971	EMILIN complex	ISO	J:164563
Cellular Component	GO:0031012	extracellular matrix	IDA	J:87574
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-2426460
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0034668	integrin alpha4-beta1 complex	ISO	J:164563
Biological Process	GO:0003180	aortic valve morphogenesis	IMP	J:215596
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0033627	cell adhesion mediated by integrin	IDA	J:177724
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0007160	cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0048251	elastic fiber assembly	IMP	J:215596
Biological Process	GO:0030198	extracellular matrix organization	IDA	J:139122
Biological Process	GO:0016525	negative regulation of angiogenesis	IMP	J:215596
Biological Process	GO:0050866	negative regulation of cell activation	IMP	J:215596
Biological Process	GO:0050866	negative regulation of cell activation	IMP	J:215596
Biological Process	GO:0032966	negative regulation of collagen biosynthetic process	IMP	J:215596
Biological Process	GO:1904027	negative regulation of collagen fibril organization	IMP	J:215596
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:215596
Biological Process	GO:1905522	negative regulation of macrophage migration	IMP	J:215596
Biological Process	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	IMP	J:215596
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	IMP	J:215596
Biological Process	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	IMP	J:215596
Biological Process	GO:0045766	positive regulation of angiogenesis	IDA	J:215596
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	IDA	J:139122
Biological Process	GO:1900426	positive regulation of defense response to bacterium	ISO	J:164563
Biological Process	GO:1901203	positive regulation of extracellular matrix assembly	IMP	J:215596
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:215596
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:215596
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:215596
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:215596
Biological Process	GO:0008217	regulation of blood pressure	IDA	J:201480
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:177724