GO Annotations Graph

• Symbol: Ppp1r15a
• Name: protein phosphatase 1, regulatory subunit 15A
• ID: MGI:1927072

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0008157	protein phosphatase 1 binding	ISO	J:164563
Molecular Function	GO:0008157	protein phosphatase 1 binding	ISO	J:155856
Molecular Function	GO:0019903	protein phosphatase binding	IDA	J:215662
Molecular Function	GO:0019888	protein phosphatase regulator activity	IDA	J:215662
Molecular Function	GO:0019888	protein phosphatase regulator activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TAS	Reactome:R-MMU-9653773
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0000164	protein phosphatase type 1 complex	ISO	J:164563
Cellular Component	GO:0000164	protein phosphatase type 1 complex	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	IMP	J:95320
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	IDA	J:217282
Biological Process	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	ISO	J:155856
Biological Process	GO:0032515	negative regulation of phosphoprotein phosphatase activity	ISO	J:164563
Biological Process	GO:0035308	negative regulation of protein dephosphorylation	ISO	J:164563
Biological Process	GO:0010955	negative regulation of protein processing	ISO	J:155856
Biological Process	GO:1903573	negative regulation of response to endoplasmic reticulum stress	IDA	J:215662
Biological Process	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	IDA	J:215662
Biological Process	GO:0070262	peptidyl-serine dephosphorylation	IDA	J:217282
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:1903917	positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:229374
Biological Process	GO:1902310	positive regulation of peptidyl-serine dephosphorylation	IDA	J:215662
Biological Process	GO:1902310	positive regulation of peptidyl-serine dephosphorylation	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	IDA	J:229374
Biological Process	GO:0032516	positive regulation of phosphoprotein phosphatase activity	ISO	J:164563
Biological Process	GO:0032516	positive regulation of phosphoprotein phosphatase activity	IBA	J:265628
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0045943	positive regulation of transcription by RNA polymerase I	IDA	J:229374
Biological Process	GO:0070972	protein localization to endoplasmic reticulum	ISO	J:164563
Biological Process	GO:0045765	regulation of angiogenesis	ISO	J:155856
Biological Process	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	IDA	J:215662
Biological Process	GO:0006417	regulation of translation	IEA	J:60000
Biological Process	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation	ISO	J:164563
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IMP	J:95320
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IBA	J:265628