GO Annotations Graph

• Symbol: Slc5a7
• Name: solute carrier family 5 (choline transporter), member 7
• ID: MGI:1927126

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0033265	choline binding	IDA	J:118185
Molecular Function	GO:0015220	choline transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015220	choline transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015220	choline transmembrane transporter activity	IMP	J:90846
Molecular Function	GO:0015220	choline transmembrane transporter activity	IDA	J:118185
Molecular Function	GO:0005307	choline:sodium symporter activity	IBA	J:265628
Molecular Function	GO:0005307	choline:sodium symporter activity	ISO	J:73065
Molecular Function	GO:0005515	protein binding	IPI	J:143819
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0045334	clathrin-coated endocytic vesicle	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0016020	membrane	NAS	J:90846
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0031594	neuromuscular junction	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	IDA	J:118185
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:118185
Cellular Component	GO:0005886	plasma membrane	ISO	J:73065
Cellular Component	GO:0044853	plasma membrane raft	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Biological Process	GO:0008292	acetylcholine biosynthetic process	ISO	J:155856
Biological Process	GO:0008292	acetylcholine biosynthetic process	ISO	J:164563
Biological Process	GO:0008292	acetylcholine biosynthetic process	IBA	J:265628
Biological Process	GO:0008292	acetylcholine biosynthetic process	IMP	J:90846
Biological Process	GO:0015871	choline transport	IBA	J:265628
Biological Process	GO:0015871	choline transport	IMP	J:90846
Biological Process	GO:0015871	choline transport	IDA	J:118185
Biological Process	GO:0001701	in utero embryonic development	IMP	J:240631
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0007274	neuromuscular synaptic transmission	IBA	J:265628
Biological Process	GO:0007274	neuromuscular synaptic transmission	IMP	J:90846
Biological Process	GO:0042136	neurotransmitter biosynthetic process	IEA	J:60000
Biological Process	GO:0006814	sodium ion transport	IEA	J:60000
Biological Process	GO:0007271	synaptic transmission, cholinergic	IBA	J:265628
Biological Process	GO:0007271	synaptic transmission, cholinergic	IMP	J:101059
Biological Process	GO:0007271	synaptic transmission, cholinergic	IMP	J:90846
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247