GO Annotations Graph

• Symbol: Git1
• Name: GIT ArfGAP 1
• ID: MGI:1927140

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043015	gamma-tubulin binding	ISO	J:164563
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:155856
Molecular Function	GO:0005096	GTPase activator activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:141061
Molecular Function	GO:0005515	protein binding	IPI	J:205503
Molecular Function	GO:0005515	protein binding	IPI	J:175149
Molecular Function	GO:0005515	protein binding	IPI	J:56615
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:155856
Molecular Function	GO:1990782	protein tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	IPI	J:120748
Molecular Function	GO:0044877	protein-containing complex binding	IPI	J:120748
Molecular Function	GO:0044877	protein-containing complex binding	IPI	J:120748
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:155856
Molecular Function	GO:0031267	small GTPase binding	ISO	J:155856
Molecular Function	GO:0031267	small GTPase binding	IBA	J:265628
Molecular Function	GO:0098879	structural constituent of postsynaptic specialization	ISO	J:155856
Cellular Component	GO:0044305	calyx of Held	IMP	J:228729
Cellular Component	GO:0044305	calyx of Held	IDA	J:228729
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-3928622
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0060077	inhibitory synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0097431	mitotic spindle pole	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0098794	postsynapse	IDA	J:205503
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0098794	postsynapse	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0098793	presynapse	IDA	J:228729
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Biological Process	GO:0007420	brain development	ISO	J:155856
Biological Process	GO:0007420	brain development	IMP	J:297321
Biological Process	GO:0007420	brain development	IBA	J:265628
Biological Process	GO:0045454	cell redox homeostasis	IMP	J:297330
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ISO	J:155856
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:297330
Biological Process	GO:0060996	dendritic spine development	ISO	J:120748
Biological Process	GO:0048013	ephrin receptor signaling pathway	IDA	J:120748
Biological Process	GO:0001771	immunological synapse formation	ISO	J:120748
Biological Process	GO:0001957	intramembranous ossification	IMP	J:297330
Biological Process	GO:0007626	locomotory behavior	IMP	J:297321
Biological Process	GO:0061743	motor learning	IMP	J:297321
Biological Process	GO:0032013	negative regulation of ARF protein signal transduction	ISO	J:155856
Biological Process	GO:0045820	negative regulation of glycolytic process	IMP	J:297330
Biological Process	GO:0106015	negative regulation of inflammatory response to wounding	IMP	J:297330
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	IMP	J:297330
Biological Process	GO:0048666	neuron development	IMP	J:297321
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	ISO	J:155856
Biological Process	GO:0090063	positive regulation of microtubule nucleation	ISO	J:164563
Biological Process	GO:2000646	positive regulation of receptor catabolic process	ISO	J:155856
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:228729
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:228729
Biological Process	GO:0032012	regulation of ARF protein signal transduction	IBA	J:265628
Biological Process	GO:0032465	regulation of cytokinesis	ISO	J:164563
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IMP	J:228729
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IDA	J:228729
Biological Process	GO:0036465	synaptic vesicle recycling	IBA	J:265628