GO Annotations Graph

• Symbol: Sav1
• Name: salvador family WW domain containing 1
• ID: MGI:1927144

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0060090	molecular adaptor activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:184223
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:72247
Biological Process	GO:0060038	cardiac muscle cell proliferation	IMP	J:170963
Biological Process	GO:0060038	cardiac muscle cell proliferation	IMP	J:170963
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:134270
Biological Process	GO:0001942	hair follicle development	IMP	J:134270
Biological Process	GO:0035329	hippo signaling	IMP	J:156531
Biological Process	GO:0035329	hippo signaling	IBA	J:265628
Biological Process	GO:0035329	hippo signaling	IMP	J:170963
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IMP	J:170963
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0060575	intestinal epithelial cell differentiation	IMP	J:134270
Biological Process	GO:0097283	keratinocyte apoptotic process	IMP	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0060487	lung epithelial cell differentiation	IMP	J:134270
Biological Process	GO:0060044	negative regulation of cardiac muscle cell proliferation	IMP	J:170963
Biological Process	GO:0008285	negative regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:134270
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:134270
Biological Process	GO:0043065	positive regulation of apoptotic process	IBA	J:265628
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:184223
Biological Process	GO:0045600	positive regulation of fat cell differentiation	IGI	J:184223
Biological Process	GO:1902174	positive regulation of keratinocyte apoptotic process	IMP	J:134270
Biological Process	GO:0050821	protein stabilization	ISO	J:184223
Biological Process	GO:0042127	regulation of cell population proliferation	IEA	J:72247
Biological Process	GO:0046620	regulation of organ growth	IMP	J:170963
Biological Process	GO:2000036	regulation of stem cell population maintenance	IMP	J:134270
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0060412	ventricular septum morphogenesis	IMP	J:170963