GO Annotations Graph

• Symbol: Pard6a
• Name: par-6 family cell polarity regulator alpha
• ID: MGI:1927223

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030742	GTP-dependent protein binding	IPI	J:113906
Molecular Function	GO:0030742	GTP-dependent protein binding	IPI	J:113906
Molecular Function	GO:0005515	protein binding	IPI	J:113906
Molecular Function	GO:0005515	protein binding	IPI	J:148693
Molecular Function	GO:0005515	protein binding	IPI	J:87877
Molecular Function	GO:0031267	small GTPase binding	IDA	J:113906
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0044295	axonal growth cone	ISO	J:155856
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:113906
Cellular Component	GO:0005938	cell cortex	IBA	J:265628
Cellular Component	GO:0005938	cell cortex	IDA	J:89290
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0030054	cell junction	TAS	Reactome:R-NUL-2161147
Cellular Component	GO:0030054	cell junction	TAS	Reactome:R-NUL-2161160
Cellular Component	GO:0030054	cell junction	TAS	Reactome:R-NUL-2161165
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:87877
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:113906
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0120157	PAR polarity complex	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0045217	cell-cell junction maintenance	IDA	J:113906
Biological Process	GO:0007098	centrosome cycle	ISO	J:164563
Biological Process	GO:0007098	centrosome cycle	IBA	J:265628
Biological Process	GO:0030010	establishment of cell polarity	TAS	J:113906
Biological Process	GO:0007163	establishment or maintenance of cell polarity	IBA	J:265628
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	ISO	J:164563
Biological Process	GO:0001933	negative regulation of protein phosphorylation	IGI	J:204152
Biological Process	GO:1904781	positive regulation of protein localization to centrosome	ISO	J:164563
Biological Process	GO:0050714	positive regulation of protein secretion	IMP	J:281253
Biological Process	GO:0060341	regulation of cellular localization	ISO	J:155856
Biological Process	GO:0060341	regulation of cellular localization	IBA	J:265628