GO Annotations Graph

• Symbol: Pals1
• Name: protein associated with LIN7 1, MAGUK family member
• ID: MGI:1927339

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0004385	guanylate kinase activity	ISS	J:64820
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:169049
Molecular Function	GO:0005515	protein binding	IPI	J:160624
Molecular Function	GO:0005515	protein binding	IPI	J:333179
Molecular Function	GO:0005515	protein binding	IPI	J:212850
Molecular Function	GO:0005515	protein binding	IPI	J:144247
Molecular Function	GO:0005515	protein binding	IPI	J:163217
Molecular Function	GO:0005515	protein binding	IPI	J:92068
Molecular Function	GO:0005515	protein binding	IPI	J:144247
Molecular Function	GO:0005515	protein binding	IPI	J:144247
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IDA	J:169049
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0045177	apical part of cell	IDA	J:220858
Cellular Component	GO:0005923	bicellular tight junction	IEA	J:60000
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0043219	lateral loop	IDA	J:159103
Cellular Component	GO:0016020	membrane	ISS	J:64820
Cellular Component	GO:0035749	myelin sheath adaxonal region	IDA	J:159103
Cellular Component	GO:0005886	plasma membrane	IDA	J:298908
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:64820
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0043220	Schmidt-Lanterman incisure	IDA	J:159103
Biological Process	GO:0021954	central nervous system neuron development	IMP	J:160624
Biological Process	GO:0021987	cerebral cortex development	IMP	J:160624
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	IBA	J:265628
Biological Process	GO:0016332	establishment or maintenance of polarity of embryonic epithelium	IBA	J:265628
Biological Process	GO:0010467	gene expression	IMP	J:114927
Biological Process	GO:0048699	generation of neurons	IBA	J:265628
Biological Process	GO:0002011	morphogenesis of an epithelial sheet	ISO	J:164563
Biological Process	GO:0002011	morphogenesis of an epithelial sheet	IBA	J:265628
Biological Process	GO:0032288	myelin assembly	ISO	J:155856
Biological Process	GO:0032287	peripheral nervous system myelin maintenance	IMP	J:159103
Biological Process	GO:0007009	plasma membrane organization	IMP	J:163217
Biological Process	GO:0008104	protein localization	IMP	J:114927
Biological Process	GO:0035750	protein localization to myelin sheath abaxonal region	IMP	J:159103
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:155856
Biological Process	GO:0072659	protein localization to plasma membrane	IBA	J:265628
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	IMP	J:169049