GO Annotations Graph

• Symbol: Xrcc2
• Name: X-ray repair complementing defective repair in Chinese hamster cells 2
• ID: MGI:1927345

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0140664	ATP-dependent DNA damage sensor activity	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0000400	four-way junction DNA binding	ISO	J:164563
Molecular Function	GO:0000400	four-way junction DNA binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:157288
Molecular Function	GO:0005515	protein binding	IPI	J:173816
Molecular Function	GO:0005515	protein binding	IPI	J:157288
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005813	centrosome	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex	ISO	J:164563
Cellular Component	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex	IBA	J:265628
Cellular Component	GO:0005657	replication fork	ISO	J:164563
Cellular Component	GO:0005657	replication fork	IBA	J:265628
Biological Process	GO:0007098	centrosome cycle	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IMP	J:105008
Biological Process	GO:0006974	DNA damage response	IMP	J:111068
Biological Process	GO:0006310	DNA recombination	IEA	J:60000
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IBA	J:265628
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IMP	J:111068
Biological Process	GO:0001701	in utero embryonic development	IMP	J:111068
Biological Process	GO:0000278	mitotic cell cycle	ISO	J:164563
Biological Process	GO:0035264	multicellular organism growth	IGI	J:120961
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:111068
Biological Process	GO:0022008	neurogenesis	IMP	J:111068
Biological Process	GO:0022008	neurogenesis	IMP	J:111068
Biological Process	GO:0022008	neurogenesis	IMP	J:120961
Biological Process	GO:0050769	positive regulation of neurogenesis	IMP	J:111068
Biological Process	GO:2000269	regulation of fibroblast apoptotic process	IGI	J:120961
Biological Process	GO:0010332	response to gamma radiation	IMP	J:111068
Biological Process	GO:0010165	response to X-ray	IMP	J:105008
Biological Process	GO:0001756	somitogenesis	IMP	J:120961
Biological Process	GO:0042148	strand invasion	ISO	J:164563
Biological Process	GO:0042148	strand invasion	IBA	J:265628