GO Annotations Graph

• Symbol: Samhd1
• Name: SAM domain and HD domain, 1
• ID: MGI:1927468

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0032567	dGTP binding	ISO	J:164563
Molecular Function	GO:0008832	dGTPase activity	ISO	J:164563
Molecular Function	GO:0008832	dGTPase activity	IDA	J:258241
Molecular Function	GO:0008832	dGTPase activity	IBA	J:265628
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0016793	triphosphoric monoester hydrolase activity	ISO	J:164563
Molecular Function	GO:0016793	triphosphoric monoester hydrolase activity	IDA	J:258241
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0035861	site of double-strand break	ISO	J:164563
Cellular Component	GO:0097197	tetraspanin-enriched microdomain	ISO	J:164563
Biological Process	GO:0046061	dATP catabolic process	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	IMP	J:202757
Biological Process	GO:0051607	defense response to virus	IBA	J:265628
Biological Process	GO:0009264	deoxyribonucleotide catabolic process	ISO	J:164563
Biological Process	GO:0006203	dGTP catabolic process	ISO	J:164563
Biological Process	GO:0006203	dGTP catabolic process	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0006260	DNA replication	IEA	J:60000
Biological Process	GO:0110025	DNA strand resection involved in replication fork processing	ISO	J:164563
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	IMP	J:202757
Biological Process	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0051289	protein homotetramerization	IDA	J:258241
Biological Process	GO:0051289	protein homotetramerization	ISO	J:164563
Biological Process	GO:0045088	regulation of innate immune response	ISO	J:164563
Biological Process	GO:0045088	regulation of innate immune response	IBA	J:265628
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	IMP	J:262069