GO Annotations Graph

• Symbol: Lsr
• Name: lipolysis stimulated lipoprotein receptor
• ID: MGI:1927471

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030228	lipoprotein particle receptor activity	TAS	J:92354
Molecular Function	GO:0030169	low-density lipoprotein particle binding	TAS	J:92354
Molecular Function	GO:0005515	protein binding	IPI	J:200231
Molecular Function	GO:0005515	protein binding	IPI	J:230002
Cellular Component	GO:0005923	bicellular tight junction	IEA	J:60000
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0042627	chylomicron	IEA	J:60000
Cellular Component	GO:0034362	low-density lipoprotein particle	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:92354
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8933256
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8933295
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0070160	tight junction	IDA	J:200231
Cellular Component	GO:0070160	tight junction	ISO	J:164563
Cellular Component	GO:0061689	tricellular tight junction	IDA	J:227374
Cellular Component	GO:0061689	tricellular tight junction	IDA	J:227364
Cellular Component	GO:0061689	tricellular tight junction	IDA	J:276413
Cellular Component	GO:0061689	tricellular tight junction	IBA	J:265628
Cellular Component	GO:0034361	very-low-density lipoprotein particle	IEA	J:60000
Biological Process	GO:0010669	epithelial structure maintenance	IDA	J:200231
Biological Process	GO:0060856	establishment of blood-brain barrier	IMP	J:227364
Biological Process	GO:0060856	establishment of blood-brain barrier	IBA	J:265628
Biological Process	GO:0061436	establishment of skin barrier	IDA	J:276413
Biological Process	GO:0042953	lipoprotein transport	TAS	J:92354
Biological Process	GO:0001889	liver development	IMP	J:92354
Biological Process	GO:0061833	protein localization to tricellular tight junction	IMP	J:276413
Biological Process	GO:0019216	regulation of lipid metabolic process	ISO	J:155856
Biological Process	GO:1904274	tricellular tight junction assembly	IMP	J:227374
Biological Process	GO:1904274	tricellular tight junction assembly	IDA	J:276413
Biological Process	GO:1904274	tricellular tight junction assembly	IBA	J:265628