GO Annotations Graph

• Symbol: Trps1
• Name: transcriptional repressor GATA binding 1
• ID: MGI:1927616

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:166026
Molecular Function	GO:0005515	protein binding	IPI	J:149459
Molecular Function	GO:0005515	protein binding	IPI	J:80674
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IEA	J:72247
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:141606
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0002062	chondrocyte differentiation	IGI	J:141606
Biological Process	GO:0002062	chondrocyte differentiation	IGI	J:141606
Biological Process	GO:0001942	hair follicle development	IMP	J:194118
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:194118
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IPI	J:80674
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:141606
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:141606
Biological Process	GO:0032330	regulation of chondrocyte differentiation	IMP	J:149459
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0001501	skeletal system development	ISO	J:164563
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	IGI	J:141606
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	IGI	J:141606
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	IGI	J:141606