GO Annotations Graph

• Symbol: Inpp5e
• Name: inositol polyphosphate-5-phosphatase E
• ID: MGI:1927753

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004445	inositol-polyphosphate 5-phosphatase activity	ISO	J:155856
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	ISO	J:155856
Molecular Function	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	IBA	J:265628
Molecular Function	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	IDA	J:63827
Molecular Function	GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	ISO	J:155856
Cellular Component	GO:0005930	axoneme	ISO	J:164563
Cellular Component	GO:0005930	axoneme	IDA	J:152712
Cellular Component	GO:0005930	axoneme	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005929	cilium	IDA	J:246963
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0000139	Golgi membrane	IDA	J:63827
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IDA	J:249381
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0001726	ruffle	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	ISO	J:155856
Biological Process	GO:1903565	negative regulation of protein localization to cilium	IMP	J:246963
Biological Process	GO:1903565	negative regulation of protein localization to cilium	IMP	J:246963
Biological Process	GO:1903565	negative regulation of protein localization to cilium	IMP	J:246963
Biological Process	GO:0017148	negative regulation of translation	ISO	J:155856
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	IBA	J:265628
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	IDA	J:63827
Biological Process	GO:0046488	phosphatidylinositol metabolic process	IDA	J:63827
Biological Process	GO:0046488	phosphatidylinositol metabolic process	IMP	J:246963