GO Annotations Graph

• Symbol: Dhodh
• Name: dihydroorotate dehydrogenase
• ID: MGI:1928378

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004151	dihydroorotase activity	IMP	J:161332
Molecular Function	GO:0004151	dihydroorotase activity	IMP	J:310328
Molecular Function	GO:0106430	dihydroorotate dehydrogenase (quinone) activity	IEA	J:72245
Molecular Function	GO:0004152	dihydroorotate dehydrogenase activity	ISO	J:155856
Molecular Function	GO:0004152	dihydroorotate dehydrogenase activity	IBA	J:265628
Molecular Function	GO:0004152	dihydroorotate dehydrogenase activity	IMP	J:161332
Molecular Function	GO:0004152	dihydroorotate dehydrogenase activity	IMP	J:307217
Molecular Function	GO:0004152	dihydroorotate dehydrogenase activity	IMP	J:307217
Molecular Function	GO:0004152	dihydroorotate dehydrogenase activity	IMP	J:161332
Molecular Function	GO:0010181	FMN binding	ISO	J:155856
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEA	J:72247
Molecular Function	GO:0048038	quinone binding	ISO	J:155856
Molecular Function	GO:0048039	ubiquinone binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:72247
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:155856
Cellular Component	GO:0005743	mitochondrial inner membrane	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Biological Process	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	ISO	J:155856
Biological Process	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	IBA	J:265628
Biological Process	GO:0044205	'de novo' UMP biosynthetic process	IMP	J:307217
Biological Process	GO:0044205	'de novo' UMP biosynthetic process	IMP	J:310326
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0006221	pyrimidine nucleotide biosynthetic process	IEA	J:60000
Biological Process	GO:0009220	pyrimidine ribonucleotide biosynthetic process	IBA	J:265628
Biological Process	GO:0090140	regulation of mitochondrial fission	ISO	J:155856
Biological Process	GO:0006225	UDP biosynthetic process	IMP	J:307217
Biological Process	GO:0006225	UDP biosynthetic process	IMP	J:310326