GO Annotations Graph

• Symbol: Snx1
• Name: sorting nexin 1
• ID: MGI:1928395

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005154	epidermal growth factor receptor binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005158	insulin receptor binding	ISO	J:164563
Molecular Function	GO:1990460	leptin receptor binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0035091	phosphatidylinositol binding	ISO	J:164563
Molecular Function	GO:0035091	phosphatidylinositol binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:208189
Molecular Function	GO:0005515	protein binding	IPI	J:93750
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:1990459	transferrin receptor binding	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	IDA	J:208189
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0005769	early endosome	IDA	J:150327
Cellular Component	GO:0031901	early endosome membrane	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	IBA	J:265628
Cellular Component	GO:0005768	endosome	IDA	J:89488
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0010008	endosome membrane	IBA	J:265628
Cellular Component	GO:0098999	extrinsic component of postsynaptic endosome membrane	IDA	J:208189
Cellular Component	GO:0098999	extrinsic component of postsynaptic endosome membrane	IDA	J:208189
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:212820
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:150327
Cellular Component	GO:0014069	postsynaptic density	IDA	J:208189
Cellular Component	GO:0099092	postsynaptic density, intracellular component	IDA	J:208189
Cellular Component	GO:0099092	postsynaptic density, intracellular component	IDA	J:208189
Cellular Component	GO:0099092	postsynaptic density, intracellular component	IDA	J:208189
Cellular Component	GO:0099092	postsynaptic density, intracellular component	IEP	J:208189
Cellular Component	GO:0098793	presynapse	IDA	J:208189
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0030904	retromer complex	ISO	J:164563
Cellular Component	GO:0030905	retromer, tubulation complex	ISO	J:164563
Cellular Component	GO:0031982	vesicle	ISO	J:164563
Biological Process	GO:0034498	early endosome to Golgi transport	ISO	J:164563
Biological Process	GO:0034498	early endosome to Golgi transport	IBA	J:265628
Biological Process	GO:0006886	intracellular protein transport	ISO	J:164563
Biological Process	GO:0072673	lamellipodium morphogenesis	ISO	J:164563
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	IDA	J:93750
Biological Process	GO:0031175	neuron projection development	IDA	J:208189
Biological Process	GO:0045732	positive regulation of protein catabolic process	ISO	J:155856
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0031623	receptor internalization	ISO	J:164563
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	ISO	J:164563