GO Annotations Graph

• Symbol: Akap8
• Name: A kinase anchor protein 8
• ID: MGI:1928488

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:73065
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0051059	NF-kappaB binding	IDA	J:230622
Molecular Function	GO:0005515	protein binding	IPI	J:230622
Molecular Function	GO:0005515	protein binding	IPI	J:116474
Molecular Function	GO:0005515	protein binding	IPI	J:116474
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	ISO	J:155856
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	ISO	J:164563
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	IBA	J:265628
Molecular Function	GO:0008270	zinc ion binding	ISO	J:155856
Cellular Component	GO:0000785	chromatin	ISO	J:73065
Cellular Component	GO:0000793	condensed chromosome	ISO	J:73065
Cellular Component	GO:0000793	condensed chromosome	IDA	J:94339
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0001939	female pronucleus	IDA	J:94339
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0016363	nuclear matrix	IDA	J:116474
Cellular Component	GO:0016363	nuclear matrix	ISO	J:155856
Cellular Component	GO:0016363	nuclear matrix	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:94339
Cellular Component	GO:0005634	nucleus	IDA	J:94339
Cellular Component	GO:0005634	nucleus	IDA	J:94339
Cellular Component	GO:0005634	nucleus	IDA	J:94339
Biological Process	GO:0044839	cell cycle G2/M phase transition	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:230622
Biological Process	GO:0071380	cellular response to prostaglandin E stimulus	IMP	J:230622
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0007076	mitotic chromosome condensation	IDA	J:94339
Biological Process	GO:0007076	mitotic chromosome condensation	ISO	J:73065
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	IMP	J:230622
Biological Process	GO:0031065	positive regulation of histone deacetylation	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000