GO Annotations Graph

• Symbol: Slc4a8
• Name: solute carrier family 4 (anion exchanger), member 8
• ID: MGI:1928745

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015297	antiporter activity	IEA	J:60000
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015108	chloride transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008509	monoatomic anion transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0015081	sodium ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0140892	sodium,bicarbonate:chloride antiporter activity	IDA	J:161474
Molecular Function	GO:0140892	sodium,bicarbonate:chloride antiporter activity	ISO	J:155856
Molecular Function	GO:0140892	sodium,bicarbonate:chloride antiporter activity	ISO	J:164563
Molecular Function	GO:0008510	sodium:bicarbonate symporter activity	ISO	J:164563
Molecular Function	GO:0008510	sodium:bicarbonate symporter activity	IBA	J:265628
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IEA	J:72247
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0032279	asymmetric synapse	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:328865
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0030425	dendrite	ISO	J:164563
Cellular Component	GO:0097386	glial cell projection	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:173358
Cellular Component	GO:0097457	hippocampal mossy fiber	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:136047
Cellular Component	GO:0016020	membrane	IDA	J:136047
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:136047
Cellular Component	GO:0032809	neuronal cell body membrane	IDA	J:136047
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:201360
Cellular Component	GO:0005886	plasma membrane	IDA	J:136047
Cellular Component	GO:0005886	plasma membrane	IDA	J:136047
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0098793	presynapse	IDA	J:173358
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:173358
Cellular Component	GO:0032280	symmetric synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:0110010	basolateral protein secretion	ISO	J:155856
Biological Process	GO:0015701	bicarbonate transport	ISO	J:164563
Biological Process	GO:0015701	bicarbonate transport	IBA	J:265628
Biological Process	GO:1902476	chloride transmembrane transport	ISO	J:164563
Biological Process	GO:0009790	embryo development	IMP	J:202055
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:173358
Biological Process	GO:0006820	monoatomic anion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:2000302	positive regulation of synaptic vesicle exocytosis	IMP	J:173358
Biological Process	GO:0051453	regulation of intracellular pH	IMP	J:173358
Biological Process	GO:0051453	regulation of intracellular pH	ISO	J:164563
Biological Process	GO:0051453	regulation of intracellular pH	ISO	J:155856
Biological Process	GO:0051453	regulation of intracellular pH	IBA	J:265628
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:164563
Biological Process	GO:0035725	sodium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006814	sodium ion transport	IEA	J:60000
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628