GO Annotations Graph

• Symbol: Cacna1h
• Name: calcium channel, voltage-dependent, T type, alpha 1H subunit
• ID: MGI:1928842

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0008332	low voltage-gated calcium channel activity	ISO	J:155856
Molecular Function	GO:0008332	low voltage-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0008332	low voltage-gated calcium channel activity	IBA	J:265628
Molecular Function	GO:0008332	low voltage-gated calcium channel activity	ISS	J:67141
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:168498
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:164563
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IEA	J:72247
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	ISO	J:164563
Molecular Function	GO:0005248	voltage-gated sodium channel activity	IBA	J:265628
Cellular Component	GO:0005901	caveola	IDA	J:168498
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:172304
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:172304
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:172304
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:172304
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-525831
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:172304
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:172304
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:172304
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:172304
Cellular Component	GO:0042383	sarcolemma	IDA	J:168498
Cellular Component	GO:0005891	voltage-gated calcium channel complex	ISS	J:67141
Cellular Component	GO:0001518	voltage-gated sodium channel complex	IBA	J:265628
Biological Process	GO:0032342	aldosterone biosynthetic process	ISO	J:155856
Biological Process	GO:0032342	aldosterone biosynthetic process	ISO	J:164563
Biological Process	GO:0070509	calcium ion import	ISO	J:155856
Biological Process	GO:0070509	calcium ion import	ISO	J:164563
Biological Process	GO:0070509	calcium ion import	IBA	J:265628
Biological Process	GO:0070588	calcium ion transmembrane transport	IEA	J:60000
Biological Process	GO:0070588	calcium ion transmembrane transport	IEA	J:72247
Biological Process	GO:0006816	calcium ion transport	ISO	J:155856
Biological Process	GO:0034651	cortisol biosynthetic process	ISO	J:164563
Biological Process	GO:0034651	cortisol biosynthetic process	ISO	J:155856
Biological Process	GO:0098662	inorganic cation transmembrane transport	ISO	J:164563
Biological Process	GO:0086010	membrane depolarization during action potential	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0019228	neuronal action potential	IBA	J:265628
Biological Process	GO:2000344	positive regulation of acrosome reaction	ISO	J:164563
Biological Process	GO:0045956	positive regulation of calcium ion-dependent exocytosis	IBA	J:265628
Biological Process	GO:0106134	positive regulation of cardiac muscle cell contraction	ISO	J:155856
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:164563
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0035725	sodium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247