GO Annotations Graph

• Symbol: Usp14
• Name: ubiquitin specific peptidase 14
• ID: MGI:1928898

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	IBA	J:265628
Molecular Function	GO:0008234	cysteine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0004866	endopeptidase inhibitor activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0061578	K63-linked deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0070628	proteasome binding	ISO	J:164563
Molecular Function	GO:0070628	proteasome binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:145150
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0000502	proteasome complex	IEA	J:60000
Cellular Component	GO:0045202	synapse	IDA	J:79322
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:79322
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IEA	J:72247
Biological Process	GO:0016579	protein deubiquitination	ISO	J:164563
Biological Process	GO:0016579	protein deubiquitination	IBA	J:265628
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0050920	regulation of chemotaxis	ISO	J:164563
Biological Process	GO:0061136	regulation of proteasomal protein catabolic process	ISO	J:164563
Biological Process	GO:0061136	regulation of proteasomal protein catabolic process	IBA	J:265628
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	J:72247