Stk4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Stk4
serine/threonine kinase 4
MGI:1929004

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:238700
Molecular Function	GO:0005515	protein binding	IPI	J:112648
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:75789
Molecular Function	GO:0004672	protein kinase activity	ISO	J:156774
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:75789
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:75789
Cellular Component	GO:0005737	cytoplasm	IDA	J:80711
Cellular Component	GO:0005737	cytoplasm	IDA	J:134270
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:134270
Cellular Component	GO:0005634	nucleus	IDA	J:80711
Cellular Component	GO:0032991	protein-containing complex	ISO	J:156774
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IGI	J:156541
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:155001
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:155001
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:156541
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:156541
Biological Process	GO:0060706	cell differentiation involved in embryonic placenta development	IGI	J:155001
Biological Process	GO:0000902	cell morphogenesis	ISO	J:75789
Biological Process	GO:0008283	cell population proliferation	IGI	J:156541
Biological Process	GO:0008283	cell population proliferation	IGI	J:156541
Biological Process	GO:0008283	cell population proliferation	IGI	J:156541
Biological Process	GO:0008283	cell population proliferation	IGI	J:155001
Biological Process	GO:0007417	central nervous system development	IGI	J:155001
Biological Process	GO:0003157	endocardium development	IGI	J:155001
Biological Process	GO:0050673	epithelial cell proliferation	IGI	J:156541
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:156541
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:156541
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:156541
Biological Process	GO:0097284	hepatocyte apoptotic process	IGI	J:156541
Biological Process	GO:0097284	hepatocyte apoptotic process	IGI	J:156541
Biological Process	GO:0035329	hippo signaling	IMP	J:156531
Biological Process	GO:0035329	hippo signaling	ISO	J:164563
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035556	intracellular signal transduction	ISO	J:164563
Biological Process	GO:0035556	intracellular signal transduction	IBA	J:265628
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IGI	J:156541
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:156541
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:155001
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IGI	J:156541
Biological Process	GO:0046621	negative regulation of organ growth	IGI	J:156541
Biological Process	GO:0001841	neural tube formation	IGI	J:155001
Biological Process	GO:0035265	organ growth	IGI	J:156541
Biological Process	GO:0035265	organ growth	IGI	J:156541
Biological Process	GO:0035265	organ growth	IGI	J:156541
Biological Process	GO:0035265	organ growth	IGI	J:156541
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	IGI	J:156541
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:156541
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:156541
Biological Process	GO:0045600	positive regulation of fat cell differentiation	IGI	J:184223
Biological Process	GO:1903945	positive regulation of hepatocyte apoptotic process	IGI	J:156541
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:156774
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:184223
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:156774
Biological Process	GO:1904237	positive regulation of substrate-dependent cell migration, cell attachment to substrate	IMP	J:142674
Biological Process	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0060215	primitive hemopoiesis	IGI	J:155001
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:75789
Biological Process	GO:0006606	protein import into nucleus	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IBA	J:265628
Biological Process	GO:0006468	protein phosphorylation	ISO	J:75789
Biological Process	GO:0050821	protein stabilization	IMP	J:156774
Biological Process	GO:0050821	protein stabilization	ISO	J:156774
Biological Process	GO:0051262	protein tetramerization	IEA	J:72247
Biological Process	GO:0060800	regulation of cell differentiation involved in embryonic placenta development	IGI	J:214531
Biological Process	GO:0043408	regulation of MAPK cascade	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IEA	J:72247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24