GO Annotations Graph

• Symbol: Pus1
• Name: pseudouridine synthase 1
• ID: MGI:1929237

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:92505
Molecular Function	GO:0016853	isomerase activity	IEA	J:60000
Molecular Function	GO:0030374	nuclear receptor coactivator activity	IDA	J:92505
Molecular Function	GO:0005515	protein binding	IPI	J:92505
Molecular Function	GO:0009982	pseudouridine synthase activity	ISO	J:164563
Molecular Function	GO:0009982	pseudouridine synthase activity	IMP	J:237107
Molecular Function	GO:0009982	pseudouridine synthase activity	IBA	J:265628
Molecular Function	GO:0009982	pseudouridine synthase activity	IMP	J:92505
Molecular Function	GO:0009982	pseudouridine synthase activity	IDA	J:85114
Molecular Function	GO:0003723	RNA binding	IEA	J:72247
Molecular Function	GO:0002153	steroid receptor RNA activator RNA binding	ISO	J:164563
Molecular Function	GO:0000049	tRNA binding	ISO	J:164563
Molecular Function	GO:0106029	tRNA pseudouridine synthase activity	IDA	J:66589
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	IDA	J:92505
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:92505
Cellular Component	GO:0005634	nucleus	IDA	J:92505
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:92505
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:1990481	mRNA pseudouridine synthesis	ISO	J:164563
Biological Process	GO:1990481	mRNA pseudouridine synthesis	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:92505
Biological Process	GO:0001522	pseudouridine synthesis	IEA	J:72247
Biological Process	GO:0009451	RNA modification	IEA	J:72247
Biological Process	GO:0008380	RNA splicing	IEA	J:60000
Biological Process	GO:0008033	tRNA processing	IEA	J:60000
Biological Process	GO:0031119	tRNA pseudouridine synthesis	ISO	J:164563
Biological Process	GO:0031119	tRNA pseudouridine synthesis	IMP	J:237107
Biological Process	GO:0031119	tRNA pseudouridine synthesis	IDA	J:66589
Biological Process	GO:0031119	tRNA pseudouridine synthesis	IBA	J:265628
Biological Process	GO:0031119	tRNA pseudouridine synthesis	IDA	J:85114
Biological Process	GO:0031119	tRNA pseudouridine synthesis	IDA	J:66334
Biological Process	GO:0031119	tRNA pseudouridine synthesis	IDA	J:92505