GO Annotations Graph

• Symbol: Kcnip3
• Name: Kv channel interacting protein 3, calsenilin
• ID: MGI:1929258

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IMP	J:240289
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0048306	calcium-dependent protein binding	IPI	J:240289
Molecular Function	GO:0048306	calcium-dependent protein binding	IPI	J:117797
Molecular Function	GO:0001046	core promoter sequence-specific DNA binding	IMP	J:240289
Molecular Function	GO:0003677	DNA binding	IDA	J:74345
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IMP	J:74345
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:74345
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0043167	ion binding	EXP	J:240289
Molecular Function	GO:0000287	magnesium ion binding	IMP	J:240289
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0140677	molecular function activator activity	EXP	J:240289
Molecular Function	GO:0005267	potassium channel activity	IEA	J:60000
Molecular Function	GO:0015459	potassium channel regulator activity	IMP	J:165494
Molecular Function	GO:0015459	potassium channel regulator activity	ISO	J:155856
Molecular Function	GO:0015459	potassium channel regulator activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:117797
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:74345
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:217984
Cellular Component	GO:0005829	cytosol	IDA	J:117797
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9640074
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9640094
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:117797
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:155856
Cellular Component	GO:0032993	protein-DNA complex	IMP	J:240289
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IDA	J:165494
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IDA	J:217990
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0048266	behavioral response to pain	IMP	J:85927
Biological Process	GO:0006886	intracellular protein transport	ISO	J:155856
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	TAS	J:67258
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:74345
Biological Process	GO:0071805	potassium ion transmembrane transport	IEA	J:60000
Biological Process	GO:0006813	potassium ion transport	TAS	J:67258
Biological Process	GO:0072659	protein localization to plasma membrane	IDA	J:217984
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0043523	regulation of neuron apoptotic process	IDA	J:117797
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	IMP	J:165494
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0032026	response to magnesium ion	IMP	J:240289
Biological Process	GO:0048265	response to pain	IMP	J:74345
Biological Process	GO:0019233	sensory perception of pain	IMP	J:74345