GO Annotations Graph

• Symbol: Mtch2
• Name: mitochondrial carrier 2
• ID: MGI:1929260

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0032977	membrane insertase activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:209127
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005743	mitochondrial inner membrane	HDA	J:100953
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	IDA	J:209127
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0071478	cellular response to radiation	IMP	J:224442
Biological Process	GO:0090152	establishment of protein localization to mitochondrial membrane involved in mitochondrial fission	IMP	J:224442
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	IMP	J:224442
Biological Process	GO:0035701	hematopoietic stem cell migration	IMP	J:224442
Biological Process	GO:0097284	hepatocyte apoptotic process	IGI	J:209127
Biological Process	GO:0097284	hepatocyte apoptotic process	IGI	J:209127
Biological Process	GO:0006089	lactate metabolic process	IMP	J:224442
Biological Process	GO:0055088	lipid homeostasis	IMP	J:314217
Biological Process	GO:0042775	mitochondrial ATP synthesis coupled electron transport	IMP	J:224442
Biological Process	GO:0045820	negative regulation of glycolytic process	IMP	J:224442
Biological Process	GO:0010917	negative regulation of mitochondrial membrane potential	IMP	J:224442
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:99100
Biological Process	GO:0043065	positive regulation of apoptotic process	IBA	J:265628
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	IMP	J:224442
Biological Process	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:224442
Biological Process	GO:2000738	positive regulation of stem cell differentiation	IMP	J:267823
Biological Process	GO:0045040	protein insertion into mitochondrial outer membrane	ISO	J:164563
Biological Process	GO:0070585	protein localization to mitochondrion	IMP	J:209127
Biological Process	GO:0070585	protein localization to mitochondrion	IMP	J:224442
Biological Process	GO:0070585	protein localization to mitochondrion	ISO	J:73065
Biological Process	GO:0070585	protein localization to mitochondrion	IMP	J:202721
Biological Process	GO:0010635	regulation of mitochondrial fusion	IMP	J:267823
Biological Process	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	IGI	J:202721
Biological Process	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	IGI	J:202721
Biological Process	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	IGI	J:209127