Tmed2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Tmed2
transmembrane p24 trafficking protein 2
MGI:1929269

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005109	frizzled binding	IPI	J:323230
Molecular Function	GO:0005515	protein binding	IPI	J:304730
Molecular Function	GO:0005119	smoothened binding	IPI	J:323230
Cellular Component	GO:0030137	COPI-coated vesicle	ISO	J:155856
Cellular Component	GO:0030134	COPII-coated ER to Golgi transport vesicle	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IDA	J:267543
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	ISO	J:164563
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	IBA	J:265628
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	IDA	J:267543
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:323230
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:323230
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0042589	zymogen granule membrane	ISO	J:155856
Biological Process	GO:1905069	allantois development	IMP	J:267543
Biological Process	GO:0060670	branching involved in labyrinthine layer morphogenesis	IMP	J:267543
Biological Process	GO:0060717	chorion development	IMP	J:267543
Biological Process	GO:0048598	embryonic morphogenesis	IMP	J:160012
Biological Process	GO:0001892	embryonic placenta development	IMP	J:160012
Biological Process	GO:0090158	endoplasmic reticulum membrane organization	IMP	J:246024
Biological Process	GO:0007029	endoplasmic reticulum organization	IMP	J:267543
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA	J:265628
Biological Process	GO:0007030	Golgi organization	ISO	J:164563
Biological Process	GO:0007030	Golgi organization	IBA	J:265628
Biological Process	GO:0001947	heart looping	IMP	J:160012
Biological Process	GO:0001947	heart looping	IMP	J:160012
Biological Process	GO:0001701	in utero embryonic development	IMP	J:160012
Biological Process	GO:0001701	in utero embryonic development	IMP	J:160012
Biological Process	GO:0006954	inflammatory response	IMP	J:304730
Biological Process	GO:0006886	intracellular protein transport	ISO	J:164563
Biological Process	GO:0006886	intracellular protein transport	IBA	J:265628
Biological Process	GO:0060716	labyrinthine layer blood vessel development	IMP	J:160012
Biological Process	GO:0072595	maintenance of protein localization in organelle	IMP	J:323230
Biological Process	GO:0001893	maternal placenta development	IMP	J:160012
Biological Process	GO:0035264	multicellular organism growth	IMP	J:160012
Biological Process	GO:0035264	multicellular organism growth	IMP	J:160012
Biological Process	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	IMP	J:246024
Biological Process	GO:0034260	negative regulation of GTPase activity	ISO	J:164563
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	IMP	J:323230
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	IMP	J:323230
Biological Process	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	IMP	J:323230
Biological Process	GO:0001843	neural tube closure	IMP	J:160012
Biological Process	GO:0036499	PERK-mediated unfolded protein response	IMP	J:246024
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:160012
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:160012
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:160012
Biological Process	GO:0090073	positive regulation of protein homodimerization activity	ISO	J:267543
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:160012
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:160012
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:160012
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:160012
Biological Process	GO:0008104	protein localization	IMP	J:267543
Biological Process	GO:0008104	protein localization	IMP	J:267543
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0009306	protein secretion	IMP	J:304730
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:2000638	regulation of SREBP signaling pathway	IMP	J:246024
Biological Process	GO:0032525	somite rostral/caudal axis specification	IMP	J:160012
Biological Process	GO:0001756	somitogenesis	IMP	J:160012
Biological Process	GO:0016192	vesicle-mediated transport	IEA	J:60000

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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