GO Annotations Graph

• Symbol: Ptges3
• Name: prostaglandin E synthase 3
• ID: MGI:1929282

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070182	DNA polymerase binding	ISO	J:164563
Molecular Function	GO:0070182	DNA polymerase binding	IPI	J:238470
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0051879	Hsp90 protein binding	ISO	J:155856
Molecular Function	GO:0051879	Hsp90 protein binding	ISO	J:164563
Molecular Function	GO:0051879	Hsp90 protein binding	IBA	J:265628
Molecular Function	GO:0016853	isomerase activity	IEA	J:60000
Molecular Function	GO:0002039	p53 binding	ISO	J:155856
Molecular Function	GO:0050220	prostaglandin-E synthase activity	ISO	J:164563
Molecular Function	GO:0050220	prostaglandin-E synthase activity	ISO	J:155856
Molecular Function	GO:0050220	prostaglandin-E synthase activity	IBA	J:265628
Molecular Function	GO:0051087	protein-folding chaperone binding	IBA	J:265628
Molecular Function	GO:0003720	telomerase activity	ISO	J:164563
Molecular Function	GO:0051082	unfolded protein binding	ISO	J:164563
Cellular Component	GO:0005884	actin filament	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0101031	protein folding chaperone complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0005697	telomerase holoenzyme complex	ISO	J:164563
Biological Process	GO:0051085	chaperone cofactor-dependent protein refolding	ISO	J:164563
Biological Process	GO:0051131	chaperone-mediated protein complex assembly	ISO	J:164563
Biological Process	GO:0051131	chaperone-mediated protein complex assembly	IBA	J:265628
Biological Process	GO:0006633	fatty acid biosynthetic process	IEA	J:60000
Biological Process	GO:0006631	fatty acid metabolic process	IEA	J:60000
Biological Process	GO:0048144	fibroblast proliferation	IMP	J:122356
Biological Process	GO:0042921	glucocorticoid receptor signaling pathway	IMP	J:122356
Biological Process	GO:0005978	glycogen biosynthetic process	IMP	J:122356
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0060430	lung saccule development	IMP	J:122356
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0042327	positive regulation of phosphorylation	ISO	J:164563
Biological Process	GO:0051973	positive regulation of telomerase activity	IDA	J:238470
Biological Process	GO:0051973	positive regulation of telomerase activity	ISO	J:164563
Biological Process	GO:0001516	prostaglandin biosynthetic process	ISO	J:164563
Biological Process	GO:0001516	prostaglandin biosynthetic process	ISO	J:155856
Biological Process	GO:0001516	prostaglandin biosynthetic process	IBA	J:265628
Biological Process	GO:0001516	prostaglandin biosynthetic process	IMP	J:122356
Biological Process	GO:0006693	prostaglandin metabolic process	ISO	J:155856
Biological Process	GO:0006457	protein folding	IBA	J:265628
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0043588	skin development	IMP	J:122356
Biological Process	GO:1905323	telomerase holoenzyme complex assembly	IDA	J:238470
Biological Process	GO:1905323	telomerase holoenzyme complex assembly	ISO	J:164563
Biological Process	GO:1905323	telomerase holoenzyme complex assembly	IBA	J:265628
Biological Process	GO:0007004	telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:0007004	telomere maintenance via telomerase	IDA	J:238470
Biological Process	GO:0007004	telomere maintenance via telomerase	IBA	J:265628