GO Annotations Graph

• Symbol: Slc22a21
• Name: solute carrier family 22 (organic cation transporter), member 21
• ID: MGI:1929481

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1901235	(R)-carnitine transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:1901235	(R)-carnitine transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0015226	carnitine transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015226	carnitine transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015226	carnitine transmembrane transporter activity	IDA	J:81891
Molecular Function	GO:0015226	carnitine transmembrane transporter activity	IDA	J:66383
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:164563
Molecular Function	GO:0015651	quaternary ammonium group transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015651	quaternary ammonium group transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015651	quaternary ammonium group transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0009925	basal plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0031526	brush border membrane	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005778	peroxisomal membrane	IDA	J:104009
Cellular Component	GO:0005777	peroxisome	IDA	J:81891
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Biological Process	GO:1902270	(R)-carnitine transmembrane transport	ISO	J:164563
Biological Process	GO:1902270	(R)-carnitine transmembrane transport	ISO	J:155856
Biological Process	GO:1900749	(R)-carnitine transport	ISO	J:164563
Biological Process	GO:1902603	carnitine transmembrane transport	IDA	J:81891
Biological Process	GO:0015879	carnitine transport	ISO	J:164563
Biological Process	GO:0015879	carnitine transport	ISO	J:155856
Biological Process	GO:0015879	carnitine transport	IDA	J:81891
Biological Process	GO:0015879	carnitine transport	IDA	J:66383
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0060731	positive regulation of intestinal epithelial structure maintenance	ISO	J:164563
Biological Process	GO:0015697	quaternary ammonium group transport	ISO	J:155856
Biological Process	GO:0015697	quaternary ammonium group transport	ISO	J:164563
Biological Process	GO:0015697	quaternary ammonium group transport	IBA	J:265628
Biological Process	GO:0009609	response to symbiotic bacterium	ISO	J:164563
Biological Process	GO:0034612	response to tumor necrosis factor	ISO	J:164563
Biological Process	GO:0034341	response to type II interferon	ISO	J:164563
Biological Process	GO:0070715	sodium-dependent organic cation transport	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247