GO Annotations Graph

• Symbol: Arhgap35
• Name: Rho GTPase activating protein 35
• ID: MGI:1929494

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0005525	GTP binding	IEA	J:72247
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0032794	GTPase activating protein binding	ISO	J:155856
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:155856
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:164563
Molecular Function	GO:0005096	GTPase activator activity	IDA	J:137942
Molecular Function	GO:0005096	GTPase activator activity	IBA	J:265628
Molecular Function	GO:0005096	GTPase activator activity	TAS	J:65296
Molecular Function	GO:0003924	GTPase activity	IEA	J:72247
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:65296
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0036064	ciliary basal body	IDA	J:232342
Cellular Component	GO:0005737	cytoplasm	IDA	J:65296
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0007411	axon guidance	IDA	J:68904
Biological Process	GO:0007413	axonal fasciculation	IMP	J:68904
Biological Process	GO:0043010	camera-type eye development	IMP	J:65296
Biological Process	GO:0016477	cell migration	IMP	J:137942
Biological Process	GO:0031668	cellular response to extracellular stimulus	IMP	J:68904
Biological Process	GO:0021955	central nervous system neuron axonogenesis	IMP	J:68904
Biological Process	GO:0030950	establishment or maintenance of actin cytoskeleton polarity	IMP	J:137942
Biological Process	GO:0030900	forebrain development	IMP	J:65296
Biological Process	GO:0007229	integrin-mediated signaling pathway	TAS	J:65296
Biological Process	GO:0030879	mammary gland development	IMP	J:178482
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IGI	J:182501
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IDA	J:90071
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IGI	J:182501
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0043116	negative regulation of vascular permeability	IMP	J:124788
Biological Process	GO:0001843	neural tube closure	IMP	J:65296
Biological Process	GO:0097485	neuron projection guidance	IMP	J:68904
Biological Process	GO:0045724	positive regulation of cilium assembly	IMP	J:232342
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	IMP	J:68904
Biological Process	GO:0010976	positive regulation of neuron projection development	IGI	J:90071
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IMP	J:137942
Biological Process	GO:0008064	regulation of actin polymerization or depolymerization	IMP	J:232342
Biological Process	GO:0050770	regulation of axonogenesis	IMP	J:68904
Biological Process	GO:0050770	regulation of axonogenesis	IBA	J:265628
Biological Process	GO:0008360	regulation of cell shape	IDA	J:65296
Biological Process	GO:0008361	regulation of cell size	IBA	J:265628
Biological Process	GO:0007266	Rho protein signal transduction	IBA	J:265628
Biological Process	GO:0007266	Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0007266	Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0044319	wound healing, spreading of cells	IMP	J:137942